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SARS-CoV-2 Spike Proteins

(SARS-CoV-2 Spike)
mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
SARS-CoV-2 Spike Protein (Super Stable Trimer) (His tag) SARS-CoV-2 Spike Protein (Super Stable Trimer) (His tag) SARS-CoV-2 Spike Protein (Super Stable Trimer) (His tag) (ABIN6953302)

Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-MALS. ELISA

SARS-CoV-2 Spike Protein (RBD) (His-Avi Tag) SARS-CoV-2 Spike Protein (RBD) (His-Avi Tag) SARS-CoV-2 Spike Protein (RBD) (His-Avi Tag) (ABIN7274399)

Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC

SARS-CoV-2 Spike Protein (N501Y, RBD) (His tag) SARS-CoV-2 Spike Protein (N501Y, RBD) (His tag) SARS-CoV-2 Spike Protein (N501Y, RBD) (His tag) (ABIN7274385)

Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

SARS-CoV-2 Spike Proteins by Grade

Find SARS-CoV-2 Spike Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SARS-CoV-2 Spike Proteins by Origin

Find SARS-CoV-2 Spike Proteins for a variety of species such as anti-SARS Coronavirus-2 (SARS-CoV-2) SARS-CoV-2 Spike, anti-SARS CoV-2 Omicron SARS-CoV-2 Spike, anti-SARS CoV-2 Delta SARS-CoV-2 Spike. The species listed below are among those available. Click on a link to go to the corresponding products.

SARS-CoV-2 Spike Proteins by Source

Here you will find SARS-CoV-2 Spike Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SARS-CoV-2 Spike Proteins by Protein Type

Here you can find SARS-CoV-2 Spike Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SARS-CoV-2 Spike Proteins by Application

Find SARS-CoV-2 Spike Proteins validated for a specific application such as ELISA, SDS, WB, Ct. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SARS-CoV-2 Spike Proteins by Biological Activity

Find SARS-CoV-2 Spike Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular SARS-CoV-2 Spike Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (2)
  • (6)
Cat. No. ABIN6953302
Quantity 50 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274399
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274385
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274387
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS CoV-2 Delta, SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7490659
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS CoV-2 Alpha, SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7490638
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN6961147
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN6953299
Quantity 200 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274402
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273901
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274871
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274395
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274386
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273900
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273903
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SARS-CoV-2 Spike Proteins

Erickson, Logsdon, Rhea, Hansen, Holden, Banks, Smith, German, Farr, Morley, Weaver, Hirsch, Kovac, Kontsekova, Baumann, Omer, Raber: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).

Meng, Zha, Zhou, Cao, Jiang, Zhu, Li, Lu, Zhang, Yang, Feng, Gu, Tang, Jiang, Li, Lavillette, Zhang: "A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy." in: PLoS pathogens, Vol. 19, Issue 1, pp. e1011085, (2023) (PubMed).

Bohnacker, Hartung, Henkel, Quaranta, Kolmert, Priller, Ud-Dean, Giglberger, Kugler, Pechtold, Yazici, Lechner, Erber, Protzer, Lingor, Knolle, Chaker, Schmidt-Weber, Wheelock, Esser-von Bieren: "Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages." in: Mucosal immunology, Vol. 15, Issue 3, pp. 515-524, (2022) (PubMed).

Bhalla, Payam, Morelli, Sharma, Johnson, Thomson, Jolly, Canfarotta: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).

Vogt, Augusto, Martina, Chang, Nasrallah, Speiser, Vogel, Bachmann, Mohsen: "Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron." in: Vaccines, Vol. 10, Issue 5, (2022) (PubMed).

Wu, Wu, Wang, Liu, Chu, Jiang, Kwong, Chow, Li, Chen: "Microfluidic particle dam for direct visualization of SARS-CoV-2 antibody levels in COVID-19 vaccinees." in: Science advances, Vol. 8, Issue 22, pp. eabn6064, (2022) (PubMed).

Arunachalam, Feng, Ashraf, Hu, Walls, Edara, Zarnitsyna, Aye, Golden, Miranda, Green, Threeton, Maness, Beddingfield, Bohm, Scheuermann, Goff, Dufour, Russell-Lodrigue, Kepl, Fiala, Wrenn et al.: "Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine. ..." in: Science translational medicine, Vol. 14, Issue 658, pp. eabq4130, (2022) (PubMed).

Schlör, Hirschberg, Amor, Meister, Arora, Pöhlmann, Hoffmann, Pfaender, Eddin, Kamhieh-Milz, Hanack: "SARS-CoV-2 neutralizing camelid heavy-chain-only antibodies as powerful tools for diagnostic and therapeutic applications." in: Frontiers in immunology, Vol. 13, pp. 930975, (2022) (PubMed).

Funari, Bhalla, Gentile: "Measuring the Radius of Gyration and Intrinsic Flexibility of Viral Proteins in Buffer Solution Using Small-Angle X-ray Scattering." in: ACS measurement science au, Vol. 2, Issue 6, pp. 547-552, (2022) (PubMed).

Yokoyama, Ichiki: "Nano-size dependence in the adsorption by the SARS-CoV-2 spike protein over gold colloid." in: Colloids and surfaces. A, Physicochemical and engineering aspects, Vol. 615, pp. 126275, (2021) (PubMed).

Aliases for SARS-CoV-2 Spike Proteins

E2 glycoprotein precursor (S) Proteins
Surface Glycoprotein (S) Proteins
E2 Proteins
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