SARS-CoV-2 Spike Products
(SARS-CoV-2 Spike)
Categories
mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
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Featured SARS-CoV-2 Spike Categories
SARS-CoV-2 Spike Antibodies
High quality antibodies with extensive validation data.
SARS-CoV-2 Spike Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SARS-CoV-2 Spike Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
SARS Coronavirus (SARS-CoV), SARS Coronavirus-2 (SARS-CoV-2)
Application
ELISA, WB, IF, IHC
Validations
- (9)
- (11)
Cat. No.
ABIN1030641
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
SARS Coronavirus-2 (SARS-CoV-2)
Application
ELISA, FACS
Validations
- (2)
Cat. No.
ABIN6964062
Quantity
100 μg
Datasheet
Datasheet
Recommended SARS-CoV-2 Spike Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
SARS Coronavirus-2 (SARS-CoV-2)
Source
HEK-293 Cells
Validations
- (2)
- (6)
Cat. No.
ABIN6953302
Quantity
50 μg
Datasheet
Datasheet
Reactivity
SARS Coronavirus-2 (SARS-CoV-2)
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274399
Quantity
100 μg
Datasheet
Datasheet
Reactivity
SARS Coronavirus-2 (SARS-CoV-2)
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274385
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SARS-CoV-2 Spike products
: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).: "A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy." in: PLoS pathogens, Vol. 19, Issue 1, pp. e1011085, (2023) (PubMed).
: "Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages." in: Mucosal immunology, Vol. 15, Issue 3, pp. 515-524, (2022) (PubMed).
: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).
: "Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron." in: Vaccines, Vol. 10, Issue 5, (2022) (PubMed).
: "Microfluidic particle dam for direct visualization of SARS-CoV-2 antibody levels in COVID-19 vaccinees." in: Science advances, Vol. 8, Issue 22, pp. eabn6064, (2022) (PubMed).
: "Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine. ..." in: Science translational medicine, Vol. 14, Issue 658, pp. eabq4130, (2022) (PubMed).
: "SARS-CoV-2 neutralizing camelid heavy-chain-only antibodies as powerful tools for diagnostic and therapeutic applications." in: Frontiers in immunology, Vol. 13, pp. 930975, (2022) (PubMed).
: "Measuring the Radius of Gyration and Intrinsic Flexibility of Viral Proteins in Buffer Solution Using Small-Angle X-ray Scattering." in: ACS measurement science au, Vol. 2, Issue 6, pp. 547-552, (2022) (PubMed).
: "Nano-size dependence in the adsorption by the SARS-CoV-2 spike protein over gold colloid." in: Colloids and surfaces. A, Physicochemical and engineering aspects, Vol. 615, pp. 126275, (2021) (PubMed).
Synonyms and alternative names related to SARS-CoV-2 Spike
E2 glycoprotein precursor (S), Surface Glycoprotein (S), E2Protein level used designations for SARS-CoV-2 Spike
- spike glycoprotein
- Peplomer protein
- S Protein
- S glycoprotein
- S-Protein
- Spike
- Spike Protein
- Spike glycoprotein
Did you look for something else?
- SARS-CoV-2 ORF8
- SARS-CoV-2 ORF7a
- SARS-CoV-2 ORF6
- SARS-CoV-2 ORF3a
- SARS-CoV-2 ORF1ab
- SARS-CoV-2 ORF10
- SARS-CoV-2 Nucleocapsid
- SARS-CoV-2 NSP9
- SARS-CoV-2 NSP8
- SARS-CoV-2 NSP7
- SARS-CoV-2 NSP6
- SARS-CoV-2 NSP5 (3CL-Pro)
- SARS-CoV-2 NSP4
- SARS-CoV-2 NSP3
- SARS-CoV-2 NSP2
- SARS-CoV-2 NSP16
- SARS-CoV-2 NSP15
- SARS-CoV-2 NSP14
- SARS-CoV-2 NSP13
- SARS-CoV-2 NSP12 (RdRP)
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