SARM1 Products
(Sterile alpha and TIR Motif Containing 1 (SARM1))
Categories
Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88- dependent pathway or non-TLR signaling. Negative regulator of NF- kappa-B and IRF activation (By similarity).
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Featured SARM1 Categories
SARM1 Antibodies
High quality antibodies with extensive validation data.
SARM1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SARM1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p), IHC (p)
Validations
- (2)
Cat. No.
ABIN1387556
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), IF, ICC, IHC
Validations
- (2)
Cat. No.
ABIN213875
Quantity
0.05 mg
Datasheet
Datasheet
Reactivity
Human
Application
IP, IHC (p), IHC
Validations
- (2)
Cat. No.
ABIN461750
Quantity
50 μg
Datasheet
Datasheet
Recommended SARM1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207518
Quantity
96 tests
Datasheet
Datasheet
Recommended SARM1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2731405
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our SARM1 products
: "Hm-MyD88 and Hm-SARM: two key regulators of the neuroimmune system and neural repair in the medicinal leech." in: Scientific reports, Vol. 5, pp. 9624, (2015) (PubMed).: "Activation of TLR3 promotes the degeneration of retinal ganglion cells by upregulating the protein levels of JNK3." in: Investigative ophthalmology & visual science, Vol. 56, Issue 1, pp. 505-14, (2015) (PubMed).
: "SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria." in: Molecular biology of the cell, Vol. 24, Issue 18, pp. 2772-84, (2013) (PubMed).
: "Excitotoxicity upregulates SARM1 protein expression and promotes Wallerian-like degeneration of retinal ganglion cells and their axons." in: Investigative ophthalmology & visual science, Vol. 54, Issue 4, pp. 2771-80, (2013) (PubMed).
: "Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus." in: Nature, Vol. 426, Issue 6965, pp. 450-4, (2003) (PubMed).
: "The Toll-IL-1 receptor adaptor family grows to five members." in: Trends in immunology, Vol. 24, Issue 6, pp. 286-90, (2003) (PubMed).
: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, (2003) (PubMed).
: "Innate immune recognition." in: Annual review of immunology, Vol. 20, pp. 197-216, (2002) (PubMed).
Synonyms and alternative names related to SARM1
sterile alpha and TIR motif containing 1 (SARM1), sterile alpha and HEAT/Armadillo motif containing 1 (Sarm1), sterile alpha and TIR motif containing 1 (Sarm1), sterile alpha and TIR motif containing 1 (sarm1), A830091I15Rik, C78606, MyD88-5, MyD885, SAMD2, Sarm, SARMProtein level used designations for SARM1
- sterile alpha and TIR motif-containing protein 1
- sterile alpha and TIR motif containing 1
- Tir-1 homolog
- SAM domain-containing protein 2
- sterile alpha and Armadillo repeat protein
- sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila
- sterile alpha motif domain-containing protein 2
- tir-1 homolog
Did you look for something else?
- SARDH
- Sarcolemma Associated Protein
- Sarcalumenin
- SAR1B
- SAR1A
- Sar1
- SAPS2
- SAPS1
- SAPCD2
- SAPCD1
- SAP30BP
- SAP30-Like
- SAP30
- SAP25
- SAP2
- SAP18
- SAP1
- SAMM50
- SAMHD1
- SAMD9L
- SARNP
- SARS Associated Spike Mosaic S
- SARS-Coronavirus Envelope Protein
- SARS-Coronavirus Membrane Protein
- SARS-Coronavirus Nonstructural Protein 8
- SARS-Coronavirus Nucleocapsid Protein
- SARS-CoV E2 Glycoprotein
- SARS-CoV NSP3
- SARS-CoV S1
- SARS-CoV S2
- SARS-CoV Spike
- SARS-CoV-2
- SARS-CoV-2 (CB6 Biosimilar)
- SARS-CoV-2 Envelope
- SARS-CoV-2 Membrane Protein
- SARS-CoV-2 NSP1
- SARS-CoV-2 NSP10
- SARS-CoV-2 NSP12 (RdRP)
- SARS-CoV-2 NSP13
- SARS-CoV-2 NSP14
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