SAFB Products
(Scaffold Attachment Factor B (SAFB))
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This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011].
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Featured SAFB Categories
SAFB Antibodies
High quality antibodies with extensive validation data.
SAFB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SAFB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IHC
Validations
- (7)
Cat. No.
ABIN7263975
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (6)
Cat. No.
ABIN2855048
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC
Validations
- (14)
Cat. No.
ABIN6147357
Quantity
100 μL
Datasheet
Datasheet
Recommended SAFB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207511
Quantity
96 tests
Datasheet
Datasheet
Recommended SAFB Proteins
Synonyms and alternative names related to SAFB
scaffold attachment factor B (SAFB), scaffold attachment factor B (Safb), scaffold attachment factor B (safb), scaffold attachment factor B S homeolog (safb.S), SAFB-like transcription modulator (LOC5570070), scaffold attachment factor B (CpipJ_CPIJ017179), Scaffold attachment factor B (Bm1_49330), scaffold attachment factor B (LOAG_00080), 3110021E02Rik, 5330423C17Rik, AU018122, D18386, E130307D12, HAP, HET, SAF-B1, SAFB, SAFB1, SAFB2, wu:fb40a03, wu:fd42g06, zgc:55387Protein level used designations for SAFB
- HSP27 ERE-TATA-binding protein
- HSP27 estrogen response element-TATA box-binding protein
- Hsp27 ERE-TATA binding protein
- SAB-B1
- SAF-B
- glutathione S-transferase fusion protein
- heat-shock protein (HSP27) estrogen response element and TATA box-binding protein
- scaffold attachment factor B1
- SAF-B1
- scaffold attachment factor B2
- scaffold attachment factor B
- scaffold attachment factor b
- Scaffold attachment factor B
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