SAE1 Products
(SUMO1 Activating Enzyme Subunit 1 (SAE1))
Categories
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].
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Featured SAE1 Categories
SAE1 Antibodies
High quality antibodies with extensive validation data.
SAE1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SAE1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SAE1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC, IP
Validations
- (7)
Cat. No.
ABIN2856922
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN564342
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6259959
Quantity
100 μL
Datasheet
Datasheet
Recommended SAE1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970456
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380924
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951062
Quantity
96 tests
Datasheet
Datasheet
Recommended SAE1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125243
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319108
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2131704
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our SAE1 products
: "Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure." in: Nature communications, Vol. 6, pp. 7229, (2015) (PubMed).: "Autoantibodies to small ubiquitin-like modifier activating enzymes in Japanese patients with dermatomyositis: comparison with a UK Caucasian cohort." in: Annals of the rheumatic diseases, Vol. 72, Issue 1, pp. 151-3, (2012) (PubMed).
: "Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1." in: The EMBO journal, Vol. 24, Issue 3, pp. 439-51, (2005) (PubMed).
: "Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10618-24, (1999) (PubMed).
: "Coupling of cell growth control and apoptosis functions of Id proteins." in: Molecular and cellular biology, Vol. 18, Issue 4, pp. 2371-81, (1998) (PubMed).
: "Id helix-loop-helix proteins in cell growth and differentiation." in: Trends in cell biology, Vol. 8, Issue 2, pp. 58-65, (1998) (PubMed).
: "Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system." in: Blood, Vol. 89, Issue 9, pp. 3155-65, (1997) (PubMed).
: "Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors." in: The EMBO journal, Vol. 16, Issue 2, pp. 332-42, (1997) (PubMed).
: "Differential interactions of Id proteins with basic-helix-loop-helix transcription factors." in: The Journal of biological chemistry, Vol. 272, Issue 32, pp. 19785-93, (1997) (PubMed).
: "The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein." in: Genes & development, Vol. 8, Issue 11, pp. 1270-84, (1994) (PubMed).
Synonyms and alternative names related to SAE1
SUMO1 activating enzyme subunit 1 (SAE1), SUMO1 activating enzyme subunit 1 (Sae1), SUMO1 activating enzyme subunit 1 L homeolog (sae1.L), SUMO1 activating enzyme subunit 1 (sae1), 2400010M20Rik, 2610044L12Rik, AL033372, aos, AOS1, Aos1p, AW743391, D7Ertd177e, HSPC140, sae2a, SUA1, Sua1, Sua1p, UBLE1A, Uble1a, uble1a, wu:fa28b04, zgc:86633Protein level used designations for SAE1
- SUMO-1 activating enzyme E1 N subunit
- SUMO-1 activating enzyme subunit 1
- SUMO-activating enzyme subunit 1
- activator of SUMO1
- sentrin/SUMO-activating protein AOS1
- ubiquitin-like 1-activating enzyme E1A
- ubiquitin-like protein SUMO-1 activating enzyme
- ubiquitin-like (sentrin) activating enzyme E1A
- ubiquitin-like 1 (sentrin) activating enzyme E1A
- ubiquitin-like 1 (sentrin) activating enzyme subunit 1
- SUMO-activating enzyme E1 N subunit
- SUMO1 activating enzyme subunit 2a
- Ubiquitin-like 1-activating enzyme E1A
- fa28b04
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