RYR1 Products
(Ryanodine Receptor 1 (Skeletal) (RYR1))
Categories
This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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Featured RYR1 Categories
RYR1 Antibodies
High quality antibodies with extensive validation data.
RYR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RYR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RYR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN7043604
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN7003086
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7168505
Quantity
100 μg
Datasheet
Datasheet
Recommended RYR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969981
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959209
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959210
Quantity
96 tests
Datasheet
Datasheet
Recommended RYR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7413430
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396766
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396763
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our RYR1 products
: "High-fructose and high-fat feeding correspondingly lead to the development of lysoPC-associated apoptotic cardiomyopathy and adrenergic signaling-related cardiac hypertrophy." in: International journal of cardiology, Vol. 215, pp. 65-76, (2016) (PubMed).: "Inhibition of ryanodine receptor 1 in fast skeletal muscle fibers induces a fast-to-slow muscle fiber type transition." in: Journal of cell science, Vol. 117, Issue Pt 25, pp. 6175-83, (2004) (PubMed).
: "Three-dimensional reconstruction of the recombinant type 3 ryanodine receptor and localization of its amino terminus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 11, pp. 6104-9, (2001) (PubMed).
: "Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons." in: The Journal of biological chemistry, Vol. 275, Issue 24, pp. 18195-200, (2000) (PubMed).
: "Long-chain acylcarnitine induces Ca2+ efflux from the sarcoplasmic reticulum." in: Journal of cardiovascular pharmacology, Vol. 36, Issue 1, pp. 14-21, (2000) (PubMed).
: "Role of ryanodine receptors in the assembly of calcium release units in skeletal muscle." in: The Journal of cell biology, Vol. 140, Issue 4, pp. 831-42, (1998) (PubMed).
: "A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function." in: The Journal of cell biology, Vol. 140, Issue 4, pp. 843-51, (1998) (PubMed).
: "Molecular interaction between ryanodine receptor and glycoprotein triadin involves redox cycling of functionally important hyperreactive sulfhydryls." in: The Journal of biological chemistry, Vol. 269, Issue 52, pp. 33028-34, (1995) (PubMed).
: "Three ryanodine receptor isoforms exist in avian striated muscles." in: Biochemistry, Vol. 32, Issue 22, pp. 5739-45, (1993) (PubMed).
: "Positioning of major tryptic fragments in the Ca2+ release channel (ryanodine receptor) resulting from partial digestion of rabbit skeletal muscle sarcoplasmic reticulum." in: The Journal of biological chemistry, Vol. 268, Issue 30, pp. 22642-9, (1993) (PubMed).
Synonyms and alternative names related to RYR1
ryanodine receptor 1 (RYR1), ryanodine receptor 1 (skeletal) (RYR1), ryanodine receptor 1a (skeletal) (ryr1a), ryanodine receptor 1 (Ryr1), ryanodine receptor 1, skeletal muscle (Ryr1), AI528790, alphaRYR, CCO, CRC, MHS, MHS1, RYDR, RYR, Ryr, RYR-1, ryr1, RYR1, Ryr1l, SKRR, skrrProtein level used designations for RYR1
- ryanodine receptor 1 (skeletal)
- ryanodine receptor type 1
- ryanodine receptor 1a (slow muscle)
- ryanodine receptor alpha isoform
- central core disease of muscle
- ryanodine receptor 1
- sarcoplasmic reticulum calcium release channel
- skeletal muscle calcium release channel
- skeletal muscle ryanodine receptor
- type 1-like ryanodine receptor
- skeletal muscle-type ryanodine receptor
- type 1 ryanodine receptor
- ryanodine receptor 1, skeletal muscle
- ryanodine receptor 1-like, skeletal muscle
- RYR-1
- calcium release channel
- halothane
- porcine stress syndrome
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- S-Adenosyl-Methionine
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