Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RYK Products

(RYK Receptor-Like Tyrosine Kinase (RYK))
The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured RYK Categories

RYK Antibodies

High quality antibodies with extensive validation data.

RYK ELISA Kits

Reliable ELISA kits for a wide range of species.

RYK Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RYK Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (4)
  • (7)
Cat. No. ABIN392050
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7174060
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (2)
Cat. No. ABIN392051
Quantity 400 μL
Datasheet Datasheet

Recommended RYK ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4886279
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884386
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730510
Quantity 96 tests
Datasheet Datasheet

Recommended RYK Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319036
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416715
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405843
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our RYK products

Povinelli, Nemeth: "Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor." in: Stem cells (Dayton, Ohio), Vol. 32, Issue 1, pp. 105-15, (2014) (PubMed).

González, Fernández-Martos, Arenas, Rodríguez: "The Ryk receptor is expressed in glial and fibronectin-expressing cells after spinal cord injury." in: Journal of neurotrauma, Vol. 30, Issue 10, pp. 806-17, (2013) (PubMed).

Santiago, Oguma, Brown, Laurence: "Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir." in: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 223-30, (2012) (PubMed).

Miyashita, Koda, Kitajo, Yamazaki, Takahashi, Kikuchi, Yamashita: "Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury." in: Journal of neurotrauma, Vol. 26, Issue 7, pp. 955-64, (2009) (PubMed).

Keeble, Halford, Seaman, Kee, Macheda, Anderson, Stacker, Cooper: "The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 21, pp. 5840-8, (2006) (PubMed).

Synonyms and alternative names related to RYK

receptor-like tyrosine kinase (RYK), receptor-like tyrosine kinase (ryk), receptor-like tyrosine kinase S homeolog (ryk.S), tyrosine-protein kinase RYK (LOC100541106), receptor-like tyrosine kinase (Ryk), AW536699, d3s3195, D3S3195, ERK-3, jtk5, JTK5, jtk5a, JTK5A, MGC114645, RYK, ryk1, RYK1, Vik, wu:fb37b12, wu:fi05b06, zgc:158381

Protein level used designations for RYK

  • RYK receptor-like tyrosine kinase
  • tyrosine kinase RYK
  • ryk receptor-like tyrosine kinase
  • receptor-like tyrosine kinase
  • tyrosine-protein kinase RYK
  • tyrosine kinase-related protein
  • tyrosine-protein kinase RYK-like
  • JTK5A protein tyrosine kinase
  • hydroxyaryl-protein kinase
  • NYK-R
  • growth factor receptor
  • kinase VIK
  • met-related kinase
You are here:
Support