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RUVBL2 Products

(RuvB-Like 2 (E. Coli) (RUVBL2))

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This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008].

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Featured RUVBL2 Categories

RUVBL2 Antibodies

High quality antibodies with extensive validation data.

RUVBL2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RUVBL2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (8)
Cat. No. ABIN1490850
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (10)
Cat. No. ABIN1490851
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (4)
Cat. No. ABIN524254
Quantity 50 μg
Datasheet Datasheet

Recommended RUVBL2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232258
Quantity 96 tests
Datasheet Datasheet

Recommended RUVBL2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319009
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319007
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124940
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our RUVBL2 products

Morwitzer, Tritsch, Cazares, Ward, Nuss, Bavari, Reid: "Identification of RUVBL1 and RUVBL2 as Novel Cellular Interactors of the Ebola Virus Nucleoprotein." in: Viruses, Vol. 11, Issue 4, (2019) (PubMed).

Maslon, Hrstka, Vojtesek, Hupp: "A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin." in: Journal of molecular biology, Vol. 404, Issue 3, pp. 418-38, (2010) (PubMed).

Barthéléry, Jaishankar, Salli, Vrana: "Reptin52 expression during in vitro neural differentiation of human embryonic stem cells." in: Neuroscience letters, Vol. 452, Issue 1, pp. 47-51, (2009) (PubMed).

Cho, Bhoumik, Broday, Ivanov, Rosenstein, Ronai: "TIP49b, a regulator of activating transcription factor 2 response to stress and DNA damage." in: Molecular and cellular biology, Vol. 21, Issue 24, pp. 8398-413, (2001) (PubMed).

Bauer, Chauvet, Huber, Usseglio, Rothbächer, Aragnol, Kemler, Pradel: "Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity." in: The EMBO journal, Vol. 19, Issue 22, pp. 6121-30, (2000) (PubMed).

Wood, McMahon, Cole: "An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc." in: Molecular cell, Vol. 5, Issue 2, pp. 321-30, (2000) (PubMed).

Ikura, Ogryzko, Grigoriev, Groisman, Wang, Horikoshi, Scully, Qin, Nakatani: "Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis." in: Cell, Vol. 102, Issue 4, pp. 463-73, (2000) (PubMed).

Parfait, Giovangrandi, Asheuer, Laurendeau, Olivi, Vodovar, Vidaud, Vidaud, Bièche: "Human TIP49b/RUVBL2 gene: genomic structure, expression pattern, physical link to the human CGB/LHB gene cluster on chromosome 19q13.3." in: Annales de génétique, Vol. 43, Issue 2, pp. 69-74, (2000) (PubMed).

Kanemaki, Kurokawa, Matsu-ura, Makino, Masani, Okazaki, Morishita, Tamura: "TIP49b, a new RuvB-like DNA helicase, is included in a complex together with another RuvB-like DNA helicase, TIP49a." in: The Journal of biological chemistry, Vol. 274, Issue 32, pp. 22437-44, (1999) (PubMed).

Synonyms and alternative names related to RUVBL2

RuvB like AAA ATPase 2 (RUVBL2), RuvB-like protein 2 (Ruvbl2), RuvB-like AAA ATPase 2 (Ruvbl2), RuvB-like AAA ATPase 2 (ruvbl2), RuvB-like protein 2 (ruvbl2), RuvB like AAA ATPase 2 L homeolog (ruvbl2.L), RuvB like AAA ATPase 2 (ruvbl2), ruvB-like 2 (LOC726816), TATA box-binding protein (HBUT_RS02095), ruvb-like 2 (HAN_2g314), ruvB-like 2 (LOC100282179), ruvB-like 2 (LOC100284260), RuvB like AAA ATPase 2 (Ruvbl2), ruvB-like helicase 2 (LOC5573243), AAEL010341, cgi-46, ECP51, ecp51, INO80J, MGC52995, MGC69398, mp47, p47, rept, REPTIN, reptin, Reptin, RUVBL2, RVB2, rvb2, TIH2, TIP48, tip48, TIP49B, tip49b, wu:fi25f01, xReptin, zreptin

Protein level used designations for RUVBL2

  • 48 kDa TATA box-binding protein-interacting protein
  • 48 kDa TBP-interacting protein
  • 51 kDa erythrocyte cytosolic protein
  • ECP-51
  • INO80 complex subunit J
  • RuvB (E coli homolog)-like 2
  • TAP54-beta
  • TIP60-associated protein 54-beta
  • erythrocyte cytosolic protein, 51-KD
  • repressing pontin 52
  • reptin52 protein
  • ruvB-like 2
  • reptin
  • RuvB-like protein 2
  • liebeskummer
  • lik
  • RuvB-like 2
  • RuvB-like 2 (E. coli)
  • ruvB-like 2-like
  • ruvb-like 2
  • RUVB2_AEDAE
  • ruvB-like helicase 2
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