RUNX3 Products
(Runt-Related Transcription Factor 3 (RUNX3))
Categories
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured RUNX3 Categories
RUNX3 Antibodies
High quality antibodies with extensive validation data.
RUNX3 ELISA Kits
Reliable ELISA kits for a wide range of species.
RUNX3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RUNX3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (p), FACS, IF (cc), IHC (p), ICC, IHC (fro)
Validations
- (1)
- (1)
Cat. No.
ABIN1714069
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (7)
Cat. No.
ABIN5611280
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN514065
Quantity
50 μg
Datasheet
Datasheet
Recommended RUNX3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959208
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative DNA-Binding ELISA
Validations
Cat. No.
ABIN5648562
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5658533
Quantity
96 tests
Datasheet
Datasheet
Recommended RUNX3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124938
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319002
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505242
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our RUNX3 products
: "MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway." in: Gene, Vol. 641, pp. 240-247, (2017) (PubMed).: "Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma." in: Journal of experimental & clinical cancer research : CR, Vol. 33, Issue 1, pp. 114, (2015) (PubMed).
: "Inactivation of RUNX3 predicts poor prognosis in esophageal squamous cell carcinoma after Ivor-Lewis esophagectomy." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 12, pp. 309, (2014) (PubMed).
: "Coexpression of Runx1 and Runx3 in mechanoreceptive dorsal root ganglion neurons." in: Developmental neurobiology, Vol. 73, Issue 6, pp. 469-79, (2013) (PubMed).
: "RUNX family: Regulation and diversification of roles through interacting proteins." in: International journal of cancer. Journal international du cancer, Vol. 132, Issue 6, pp. 1260-71, (2013) (PubMed).
: "Runx3-mediated transcriptional program in cytotoxic lymphocytes." in: PLoS ONE, Vol. 8, Issue 11, pp. e80467, (2013) (PubMed).
: "Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity." in: Nature immunology, Vol. 14, Issue 3, pp. 271-80, (2013) (PubMed).
: "Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks." in: The Journal of experimental medicine, Vol. 210, Issue 13, pp. 2967-80, (2013) (PubMed).
: "Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord." in: Developmental biology, Vol. 364, Issue 2, pp. 114-27, (2012) (PubMed).
: "Differential transcription factor use by the KIR2DL4 promoter under constitutive and IL-2/15-treated conditions." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4394-404, (2012) (PubMed).
Synonyms and alternative names related to RUNX3
runt-related transcription factor 3 (runx3), runt-related transcription factor 3 (RUNX3), runt related transcription factor 3 (RUNX3), runt related transcription factor 3 (runx3), runt related transcription factor 3 L homeolog (runx3.L), runt related transcription factor 3 (Runx3), runt-related transcription factor 3 (Runx3), aml2, AML2, CBFA3, cbfa3, Cbfa3, frrunx3, Pebp2a3, pebp2ac, PEBP2aC, RUNX3, runx3, runxbProtein level used designations for RUNX3
- runt-related transcription factor b
- runt-related transcription factor 3
- core-binding factor 3
- frRunx3/p45
- CBF-alpha-3
- PEA2-alpha C
- PEBP2-alpha C
- SL3-3 enhancer factor 1 alpha C subunit
- SL3/AKV core-binding factor alpha C subunit
- acute myeloid leukemia 2 protein
- core binding factor alpha 3
- core-binding factor subunit alpha-3
- oncogene AML-2
- polyomavirus enhancer-binding protein 2 alpha C subunit
- runt domain, alpha subunit 3
- transcription factor AML2/CBFA3
- PEA2 alpha C
- PEBP2 alpha C
- acute myeloid leukemia gene 2
- core-binding factor, runt domain, alpha subunit 3
- transcription factor AML2
- Runt related transcription factor 3
- Runx3 MASN-variant
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