RUNX1 Products
(Runt-Related Transcription Factor 1 (RUNX1))
Categories
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured RUNX1 Categories
RUNX1 Antibodies
High quality antibodies with extensive validation data.
RUNX1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RUNX1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RUNX1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (2)
- (5)
Cat. No.
ABIN514054
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (9)
Cat. No.
ABIN6147309
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN3022804
Quantity
100 μL
Datasheet
Datasheet
Recommended RUNX1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380825
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380155
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380156
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended RUNX1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (2)
Cat. No.
ABIN2731253
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318992
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7420045
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our RUNX1 products
: "Runt-related transcription factor 1 promotes apoptosis and inhibits neuroblastoma progression in vitro and in vivo." in: Journal of experimental & clinical cancer research : CR, Vol. 39, Issue 1, pp. 52, (2020) (PubMed).: "Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers." in: EBioMedicine, Vol. 8, pp. 117-31, (2016) (PubMed).
: "MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5." in: Cellular signalling, Vol. 27, Issue 1, pp. 156-67, (2015) (PubMed).
: "hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3." in: Cancer cell international, Vol. 14, pp. 73, (2014) (PubMed).
: "Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer." in: PLoS ONE, Vol. 9, Issue 6, pp. e100759, (2014) (PubMed).
: "Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells." in: Microvascular research, Vol. 97, pp. 55-64, (2014) (PubMed).
: "Brain death induces the alteration of liver protein expression profiles in rabbits." in: International journal of molecular medicine, Vol. 34, Issue 2, pp. 578-84, (2014) (PubMed).
: "The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion." in: Cell cycle (Georgetown, Tex.), Vol. 12, Issue 6, pp. 972-86, (2013) (PubMed).
: "Transcription factor Runx2 is a regulator of epithelial-mesenchymal transition and invasion in thyroid carcinomas." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 92, Issue 8, pp. 1181-90, (2012) (PubMed).
: "Runx1: no longer just for leukemia." in: The EMBO journal, Vol. 31, Issue 21, pp. 4098-9, (2012) (PubMed).
Synonyms and alternative names related to RUNX1
uncharacterized LOC473981 (LOC473981), runt-related transcription factor (runt), runt related transcription factor 1 (Runx1), runt related transcription factor 1 (RUNX1), runt-related transcription factor 1 (runx1), runt related transcription factor 1 L homeolog (runx1.L), runt-related transcription factor 1 (RUNX1), runt-related transcription factor 1 (Runx1), AI462102, aml, aml-1, AML1, aml1, Aml1, AML1-EVI-1, aml1-evi-1, AMLCR1, amlcr1, Cbfa2, CBFA2, cbfa2, EVI-1, evi-1, Pebp2a2, PEBP2aB, pebp2ab, Pebpa2b, Runx-1, RUNX1, runx1, runxa, XAML, Xaml1Protein level used designations for RUNX1
- runt-related transcription factor 1
- runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)
- runt-related transcription factor
- runt protein
- CBF-alpha-2
- PEA2-alpha B
- PEBP2-alpha B
- SL3-3 enhancer factor 1 alpha B subunit
- SL3/AKV core-binding factor alpha B subunit
- acute myeloid leukemia 1 protein
- core binding factor alpha 2
- core-binding factor subunit alpha-2
- oncogene AML-1
- polyomavirus enhancer-binding protein 2 alpha B subunit
- runt domain, alpha subunit 2
- AML1-EVI-1 fusion protein
- core-binding factor, runt domain, alpha subunit 2
- aml1
- runt-related transcription factor a
- runx1a
- Acute myeloid leukemia 1 protein
- Core-binding factor subunit alpha-2
- aml1 oncogene
- ch-runtB2
- acute myeloid leukemia 1
- factor, runt domain, alpha subunit 2
- core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene)
- runt related transcription factor 1
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