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RSPH4A Products

(Radial Spoke Head 4 Homolog A (RSPH4A))

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This gene encodes a protein that appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes, which are regularly spaced along cilia, sperm, and flagella axonemes, consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].

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Featured RSPH4A Categories

RSPH4A Antibodies

High quality antibodies with extensive validation data.

Recommended RSPH4A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC
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Cat. No. ABIN1386194
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (fro), IHC (p)
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Cat. No. ABIN1391473
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
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Cat. No. ABIN1391469
Quantity 100 μL
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Recommended RSPH4A Proteins

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Reactivity
Source
Validations
Cat. No.
Quantity
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3095178
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136319
Quantity 1 mg
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Latest Publications for our RSPH4A products

Onoufriadis, Shoemark, Schmidts, Patel, Jimenez, Liu, Thomas, Dixon, Hirst, Rutman, Burgoyne, Williams, Scully, Bolard, Lafitte, Beales, Hogg, Yang, Chung, Emes, OCallaghan, Bouvagnet, Mitchison: "Targeted NGS gene panel identifies mutations in RSPH1 causing primary ciliary dyskinesia and a common mechanism for ciliary central pair agenesis due to radial spoke defects." in: Human molecular genetics, Vol. 23, Issue 13, pp. 3362-74, (2014) (PubMed).

Synonyms and alternative names related to RSPH4A

radial spoke head 4 homolog A (RSPH4A), radial spoke head 4 homolog A (Chlamydomonas) (Rsph4a), radial spoke head 4 homolog A (Rsph4a), A230081C05, CILD11, dJ412I7.1, RSHL3, Rshl3, RSPH6B

Protein level used designations for RSPH4A

  • radial spoke head protein 4 homolog A
  • radial spoke head-like protein 3
  • radial spokehead-like 3
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