RRM2 Products
(Ribonucleotide Reductase M2 (RRM2))
Categories
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009].
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Featured RRM2 Categories
RRM2 Antibodies
High quality antibodies with extensive validation data.
RRM2 ELISA Kits
Reliable ELISA kits for a wide range of species.
RRM2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RRM2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IP, IHC (p)
Validations
- (5)
- (6)
Cat. No.
ABIN562744
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (1)
- (3)
Cat. No.
ABIN2855573
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (4)
Cat. No.
ABIN6147265
Quantity
100 μL
Datasheet
Datasheet
Recommended RRM2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6969960
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969959
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1155808
Quantity
96 tests
Datasheet
Datasheet
Recommended RRM2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667014
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318902
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318904
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our RRM2 products
: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).: "APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions." in: Thyroid : official journal of the American Thyroid Association, Vol. 27, Issue 1, pp. 59-66, (2016) (PubMed).
: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).
: "The expression of ribonucleotide reductase M2 in the carcinogenesis of uterine cervix and its relationship with clinicopathological characteristics and prognosis of cancer patients." in: PLoS ONE, Vol. 9, Issue 3, pp. e91644, (2015) (PubMed).
: "RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress." in: Cancer letters, Vol. 346, Issue 2, pp. 249-56, (2014) (PubMed).
: "Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins." in: PLoS ONE, Vol. 8, Issue 3, pp. e58456, (2013) (PubMed).
: "KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines." in: Anticancer research, Vol. 31, Issue 7, pp. 2535-9, (2011) (PubMed).
: "Epstein-Barr virus episome stability is coupled to a delay in replication timing." in: Journal of virology, Vol. 83, Issue 5, pp. 2154-62, (2009) (PubMed).
: "Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in ..." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 11, pp. 1952-67, (2007) (PubMed).
: "Identification of ribonucleotide reductase protein R1 as an activator of microtubule nucleation in Xenopus egg mitotic extracts." in: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4173-87, (2000) (PubMed).
Synonyms and alternative names related to RRM2
ribonucleotide reductase regulatory subunit M2 (RRM2), ribonucleotide reductase M2 (Rrm2), ribonucleotide reductase regulatory subunit M2 (Rrm2), ribonucleotide reductase M2, gene 2 L homeolog (rrm2.2.L), ribonucleotide reductase M2, gene 1 (rrm2.1), ribonucleotide reductase regulatory subunit M2 (rrm2), ribonucleotide reductase M2 polypeptide (rrm2), AA407299, cb111, chunp6884, R2, r2, RR2, RR2M, rr2m, rrm2Protein level used designations for RRM2
- ribonucleoside-diphosphate reductase subunit M2
- ribonucleotide reductase M2 polypeptide
- ribonucleotide reductase small chain
- ribonucleotide reductase small subunit
- ribonucleoside-diphosphate reductase M2 chain
- Ribonucleotide reductase 2
- etID309896.20
- reductase M2 polypeptide variant 1
- reductase M2 polypeptide variant 2
- reductase M2 polypeptide variant 3a
- reductase M2 polypeptide variant 3b
- reductase M2 polypeptide variant 3c
- reductase M2 polypeptide variant 3d
- ribonucleotide reductase protein r2 class I
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