RRM1 Products
(Ribonucleotide Reductase M1 (RRM1))
Categories
This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008].
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Featured RRM1 Categories
RRM1 Antibodies
High quality antibodies with extensive validation data.
RRM1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RRM1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RRM1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (7)
Cat. No.
ABIN7193575
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (7)
Cat. No.
ABIN3021563
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7436186
Quantity
100 μL
Datasheet
Datasheet
Recommended RRM1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969958
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959185
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959186
Quantity
96 tests
Datasheet
Datasheet
Recommended RRM1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318900
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318898
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408315
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our RRM1 products
: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).: "Bcl2 induces DNA replication stress by inhibiting ribonucleotide reductase." in: Cancer research, Vol. 74, Issue 1, pp. 212-23, (2014) (PubMed).
: "The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabine-loaded micelles on drug resistance caused by RRM1 overexpression." in: Biomaterials, Vol. 34, Issue 9, pp. 2327-39, (2013) (PubMed).
: "Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 157, Issue 1, pp. 132-40, (2012) (PubMed).
: "Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells." in: Cancer biology & therapy, Vol. 13, Issue 10, pp. 908-14, (2012) (PubMed).
: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
Synonyms and alternative names related to RRM1
ribonucleotide reductase catalytic subunit M1 (RRM1), Ribonucleoside diphosphate reductase large subunit (RnrL), ribonucleoside-diphosphate reductase large subunit (LOC100472317), ribonucleotide reductase catalytic subunit M1 (rrm1), ribonucleotide reductase M1 L homeolog (rrm1.L), ribonucleotide reductase M1 (Rrm1), ribonucleotide reductase catalytic subunit M1 (Rrm1), ribonucleotide reductase M1 (RRM1), ribonucleotide reductase M1 polypeptide (rrm1), cb396, cb838, CG5371, CHUNP6866, Dmel\\CG5371, DmRNR1, l(2)k06709, R1, r1, RIR1, RNR1, RnrM1, RntL, RR1, sb:cb548, wu:fb39b07, wu:fi14b02, wu:fk95f07, XRRM1Protein level used designations for RRM1
- ribonucleoside diphosphate reductase large subunit
- CG5371-PA
- RnrL-PA
- ribonucleoside diphosphate reductase M1 subunit
- ribonucleoside-diphosphate reductase large subunit
- ribonucleoside-diphosphate reductase M1 chain
- ribonucleotide reductase M1 polypeptide
- ribonucleotide reductase M1
- ribonucleoside-diphosphate reductase large subunit-like
- ribonucleoside-diphosphate reductase subunit M1
- ribonucleotide reductase, R1 subunit
- ribonucleotide reductase large subunit
- ribonucleotide reductase protein r1 class I
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