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RPS6KB1 Products

(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Categories

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].

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Featured RPS6KB1 Categories

RPS6KB1 Antibodies

High quality antibodies with extensive validation data.

RPS6KB1 ELISA Kits

Reliable ELISA kits for a wide range of species.

RPS6KB1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RPS6KB1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (2)
  • (6)
Cat. No. ABIN3023169
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (6)
Cat. No. ABIN6255636
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS
Validations
  • (2)
  • (5)
Cat. No. ABIN969565
Quantity 100 μL
Datasheet Datasheet

Recommended RPS6KB1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969966
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6959191
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380675
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended RPS6KB1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124903
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318840
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318838
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our RPS6KB1 products

Guo, Liu, Bow, Cui, Zhang, Xu, Lu, Tian: "The protective effect and mechanism of rapamycin in the rat model of IgA nephropathy." in: Renal failure, Vol. 41, Issue 1, pp. 334-339, (2019) (PubMed).

Xu, Wei, Li, Yin, Yuan, Yang, Zhao, Wu: "TAZ inhibition restores sensitivity of cisplatin via AKT/mTOR signaling in lung adenocarcinoma." in: Oncology reports, Vol. 38, Issue 3, pp. 1815-1821, (2018) (PubMed).

Wu, Zhu, Yin, Kang, Cao, Tian, Zhang, Lu, Liu: "Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer." in: Cancer medicine, Vol. 7, Issue 4, pp. 1546-1559, (2018) (PubMed).

Wu, Zhu, Zhang, Yin, Kang, Cao, Tian, Lu, Liu: "EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer." in: Molecular medicine reports, Vol. 17, Issue 6, pp. 7875-7885, (2018) (PubMed).

Jin, Hu, Ye, Wu, He: "Rapamycin Reduces Podocyte Apoptosis and is Involved in Autophagy and mTOR/ P70S6K/4EBP1 Signaling." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 48, Issue 2, pp. 765-772, (2018) (PubMed).

Li, Qiu, Liu, Wang, Hu, Gan, Wang: "Long-term thermal manipulation in the late incubation period can inhibit breast muscle development by activating endoplasmic reticulum stress in duck (Anasplatyrhynchos domestica)." in: Journal of thermal biology, Vol. 70, Issue Pt B, pp. 37-45, (2017) (PubMed).

Sakamoto, Miyara, Sanoh, Ohta, Kotake: "Mild MPP+exposure-induced glucose starvation enhances autophagosome synthesis and impairs its degradation." in: Scientific reports, Vol. 7, pp. 46668, (2017) (PubMed).

Zheng, Wei, Cheng, Xiang, Pang, Peng: "Supplementation of branched-chain amino acids to a reduced-protein diet improves growth performance in piglets: involvement of increased feed intake and direct muscle growth-promoting effect." in: The British journal of nutrition, Vol. 115, Issue 12, pp. 2236-45, (2017) (PubMed).

Wu, Huang, Jiao, Ding, Zhang, Chen, Wang, Li, Huo: "Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells." in: Oncotarget, Vol. 8, Issue 51, pp. 88630-88644, (2017) (PubMed).

Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).

Synonyms and alternative names related to RPS6KB1

ribosomal protein S6 kinase B1 (RPS6KB1), Ribosomal protein S6 kinase (S6k), ribosomal protein S6 kinase, polypeptide 1 (Rps6kb1), ribosomal protein S6 kinase B1 (Rps6kb1), ribosomal protein S6 kinase B1 L homeolog (rps6kb1.L), ribosomal protein S6 kinase B1 S homeolog (rps6kb1.S), ribosomal protein S6 kinase b, polypeptide 1b (rps6kb1b), 70kDa, 7084, 10539, 2610318I15Rik, 4732464A07Rik, AA959758, AI256796, AI314060, CG10539, Dmel\\CG10539, Dp70S6k, Dp70s6k, dp70s6k, Dp70[s6k], dp70[S6k], dps6k, DS6K, dS6K, dS6k, ds6k, fc51h01, fs(3)07084, l(3)07084, p70 S6K, p70 S6KA, p70(S6K)-alpha, p70-alpha, p70-S6K, p70-s6k, p70/85s6k, p70/S6K, p70S6K, p70s6K, p70s6k, p70s6k-A, p70[S6 kinase], p70[S6kinase], p70[S6K], p70[S6k], PS6K, ps6k, rps6kb1, rps6kb1-A, S6K, S6k, s6k, S6K-beta-1, S6K1, s6K1, s6k11, STK14A, stk14a, wu:fc51h01, zgc:55713

Protein level used designations for RPS6KB1

  • p70 S6 kinase, alpha
  • ribosomal protein S6 kinase I
  • ribosomal protein S6 kinase beta-1
  • serine/threonine kinase 14 alpha
  • serine/threonine-protein kinase 14A
  • CG10539-PA
  • CG10539-PB
  • S6 kinase
  • S6-kinase
  • S6k-PA
  • S6k-PB
  • S6kinase
  • dS6 kinase
  • p70 S6 kinase
  • p70 ribosomal S6 kinase
  • ribosomal S6 protein kinase
  • ribosomal protein S6 kinase
  • 70 kDa ribosomal protein S6 kinase 1
  • P70S6K1
  • S6K
  • S6K-beta-1
  • p70 S6 kinase alpha
  • p70 S6K-alpha
  • p70 S6KA
  • p70 ribosomal S6 kinase alpha
  • p70-S6K 1
  • ribosomal protein S6 kinase, 70kD, polypeptide 1
  • P70S6K
  • S6K1
  • p70(S6K)-alpha
  • ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • p70S6K
  • G3 serine/threonine kinase
  • ribosomal protein S6 kinase polypeptide 1
  • ribosomal protein S6 kinase B1 S homeolog
  • ribosomal protein S6 kinase, 70kDa, polypeptide 1 S homeolog
  • LOW QUALITY PROTEIN: ribosomal protein S6 kinase beta-1
  • ribosomal protein S6 kinase 1
  • ribosomal protein S6 kinase b, polypeptide 1
  • ribosomal protein S6 kinase, polypeptide 1
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