RPL7A Products
(Ribosomal Protein L7a (RPL7A))
Categories
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].
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Featured RPL7A Categories
RPL7A Antibodies
High quality antibodies with extensive validation data.
RPL7A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RPL7A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN6147151
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN7257329
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC
Validations
- (3)
Cat. No.
ABIN6147150
Quantity
100 μL
Datasheet
Datasheet
Recommended RPL7A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207398
Quantity
96 tests
Datasheet
Datasheet
Recommended RPL7A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318667
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2131616
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5853975
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our RPL7A products
: "Tracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA Granules." in: PLoS genetics, Vol. 12, Issue 7, pp. e1006192, (2016) (PubMed).: "Molecular dynamics of FMRP and other RNA-binding proteins in MEG-01 differentiation: the role of mRNP complexes in non-neuronal development." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 94, Issue 6, pp. 597-608, (2016) (PubMed).
: "Unusual subcellular confinement of the fragile X mental retardation protein (FMRP) in circulating human platelets: complete polyribosome dissociation." in: Biochimie, Vol. 94, Issue 4, pp. 1069-73, (2012) (PubMed).
: "Functional Sindbis virus replicative complexes are formed at the plasma membrane." in: Journal of virology, Vol. 84, Issue 22, pp. 11679-95, (2010) (PubMed).
Synonyms and alternative names related to RPL7A
Ribosomal protein L7A (RpL7A), 60S ribosomal protein L7a (LOC100525692), ribosomal protein L7a (rpl7a), ribosomal protein L7a (RPL7A), ribosomal protein L7A (Rpl7a), ribosomal protein L7a (Rpl7a), CG3314, Dmel\\CG3314, L7A, L7a, Rp L7A, rpl7a, Surf-3/rpL7a, surf3, SURF3, Surf3, Surf3/rpL7a, TRUP, wu:fa95b03, zgc:73183, zgc:86667Protein level used designations for RPL7A
- CG3314-PA
- CG3314-PD
- RpL7A-PA
- RpL7A-PD
- ribosomal protein L7A
- 60S ribosomal protein L7a
- Surfeit locus protein 3
- ribosomal protein L7a
- PLA-X polypeptide
- surfeit 3
- surfeit locus protein 3
- thyroid hormone receptor uncoupling protein
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