RP1 Products
(Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1))
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This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels, this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Two transcript variants encoding distinct isoforms are resulted from alternative promoters and alternative splicing. [provided by RefSeq, Sep 2010].
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Featured RP1 Categories
RP1 Antibodies
High quality antibodies with extensive validation data.
Recommended RP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC
Validations
Cat. No.
ABIN1386374
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (fro), IHC (p)
Validations
Cat. No.
ABIN1388857
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1388854
Quantity
100 μL
Datasheet
Datasheet
Recommended RP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422604
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422817
Quantity
100 μg
Datasheet
Datasheet
Synonyms and alternative names related to RP1
RP1, axonemal microtubule associated L homeolog (rp1.L), RP1, axonemal microtubule associated (RP1), retinitis pigmentosa 1 (autosomal dominant) (rp1), uncharacterized LOC100355685 (LOC100355685), RP1, axonemal microtubule associated (Rp1), retinitis pigmentosa 1 (human) (Rp1), Dcdc3, DCDC4A, mG145, MGC83581, orp1, ORP1, Orp1, Rp1hProtein level used designations for RP1
- retinitis pigmentosa 1 (autosomal dominant)
- retinitis pigmentosa RP1 protein
- oxygen-regulated protein 1-like
- oxygen-regulated protein 1
- retinitis pigmentosa 1 protein
- retinitis pigmentosa RP1 protein homolog
- retinitis pigmentosa 1 homolog
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