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ROCK2 Products

(rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008].

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Featured ROCK2 Categories

ROCK2 Antibodies

High quality antibodies with extensive validation data.

ROCK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

ROCK2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ROCK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7434197
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP, IF, IHC (p), ICC, IHC (fro)
Validations
  • (7)
Cat. No. ABIN2855440
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN522961
Quantity 100 μg
Datasheet Datasheet

Recommended ROCK2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962158
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959166
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959167
Quantity 96 tests
Datasheet Datasheet

Recommended ROCK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124867
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318433
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505071
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ROCK2 products

Pronobis, Zheng, Singh, Goldman, Poss: "In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration." in: eLife, Vol. 10, (2021) (PubMed).

Achiron, Feldman, Karmona, Avizemer, Barequet, Rosner, Knyazer, Bartov, Burgansky, Vishnevskia-Dai: "Prophylactic exposure of human corneal endothelial cells to Rho-associated kinase inhibitor reduced apoptosis rate after phacoemulsification: Ex vivo study." in: Journal of cataract and refractive surgery, Vol. 44, Issue 10, pp. 1261-1266, (2019) (PubMed).

Zhu, Gao, Zheng, Shui, Yu, Liu, Lin, Su, Yang, Wang: "Design and evaluation of EphrinA1 mutants with cerebral protective effect." in: Scientific reports, Vol. 7, Issue 1, pp. 1881, (2018) (PubMed).

Schwarz, Prieler, Schmid, Grzmil, Neesen: "Ccdc181 is a microtubule-binding protein that interacts with Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia." in: European journal of cell biology, Vol. 96, Issue 3, pp. 276-288, (2018) (PubMed).

He, Wei, Du, Meng, Zheng, Lai, Yao, Zhou, Wang, Luo, Ma, Zhang: "Transcription of HOTAIR is regulated by RhoC-MRTF-A-SRF signaling pathway in human breast cancer cells." in: Cellular signalling, Vol. 31, pp. 87-95, (2017) (PubMed).

Pandey, Kumari, Ali, Pasha: "Acute hypobaric hypoxia augments ROCK2 protein level and activity." in: Experimental lung research, Vol. 43, Issue 4-5, pp. 181-186, (2017) (PubMed).

Akhtar, Yousif, Dhaunsi, Sarkhouh, Chandrasekhar, Attur, Benter: "Activation of ErbB2 and Downstream Signalling via Rho Kinases and ERK1/2 Contributes to Diabetes-Induced Vascular Dysfunction." in: PLoS ONE, Vol. 8, Issue 6, pp. e67813, (2017) (PubMed).

Han, Yang, Li, Li, Zheng, Yu, Zhang, Zheng, Yi, Li, Guo, Zhou: "RhoB/ROCK mediates oxygen-glucose deprivation-stimulated syncytiotrophoblast microparticle shedding in preeclampsia." in: Cell and tissue research, Vol. 366, Issue 2, pp. 411-425, (2016) (PubMed).

Qiao, Zou, Liu, Zhu, Wang, Yang, Jiang, Chen: "ROCK2 mediates the proliferation of pulmonary arterial endothelial cells induced by hypoxia in the development of pulmonary arterial hypertension." in: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2567-2572, (2016) (PubMed).

Al-Shboul, Mustafa: "Effect of oxidative stress on Rho kinase II and smooth muscle contraction in rat stomach." in: Canadian journal of physiology and pharmacology, Vol. 93, Issue 6, pp. 405-11, (2015) (PubMed).

Synonyms and alternative names related to ROCK2

Rho-associated, coiled-coil containing protein kinase 2 L homeolog (rock2.L), rho-associated, coiled-coil containing protein kinase 2a (rock2a), Rho associated coiled-coil containing protein kinase 2 (ROCK2), Rho-associated, coiled-coil containing protein kinase 2 (ROCK2), Rho-associated coiled-coil containing protein kinase 2 (Rock2), Rho associated coiled-coil containing protein kinase 2 (Rock2), B230113H15Rik, mKIAA0619, Rho-kinase, Rock-II, ROCK-II, rock2, ROCK2, Rock2m, rocka-a, ROK, rok2, ROKalpha, xROK

Protein level used designations for ROCK2

  • Rho-associated kinase alpha
  • rho-associated protein kinase 2
  • rho-associated, coiled-coil containing protein kinase 2
  • Rho-associated, coiled-coil containing protein kinase 2
  • rho-associated protein kinase 2-like
  • Rho-associated coiled-coil forming kinage 2
  • p164 ROCK-2
  • rho-associated, coiled-coil-containing protein kinase 2
  • rho-associated, coiled-coil-containing protein kinase II
  • ROKalpha
  • Rho-associated coiled-coil forming kinase 2
  • RhoA - binding serine/threosine kinase alpha (ROK - alpha)
  • p150 ROK-alpha
  • rhoA-binding kinase 2
  • Rho-kinase alpha
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