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ROBO4 Products

(Roundabout, Axon Guidance Receptor, Homolog 4 (ROBO4))
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity).

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Featured ROBO4 Categories

ROBO4 Antibodies

High quality antibodies with extensive validation data.

ROBO4 ELISA Kits

Reliable ELISA kits for a wide range of species.

ROBO4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ROBO4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN714866
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN651292
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
  • (1)
Cat. No. ABIN2443871
Quantity 100 μL
Datasheet Datasheet

Recommended ROBO4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6976011
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969975
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973549
Quantity 96 tests
Datasheet Datasheet

Recommended ROBO4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275523
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7275524
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124933
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our ROBO4 products

Pircher, Schäfer, Eigentler, Pichler, Puhr, Steiner, Horninger, Gunsilius, Klocker, Heidegger: "Robo 4 - the double-edged sword in prostate cancer: impact on cancer cell aggressiveness and tumor vasculature." in: International journal of medical sciences, Vol. 16, Issue 1, pp. 115-124, (2019) (PubMed).

Zhang, Prahst, Mathivet, Pibouin-Fragner, Zhang, Genet, Tong, Dubrac, Eichmann: "The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization." in: Nature communications, Vol. 7, pp. 13517, (2016) (PubMed).

Chen, Hou, Tang, Jhuang, Lai, Lee, Kuo, Chou, Liu, Lin, Chuang, Chen, Tseng, Huang, Chiang, Lee, Liu, Liu, Yao, Huang, Ko, Hsu, Wu, Tsay, Chen, Tien: "Clinical and prognostic implications of Roundabout 4 (robo4) in adult patients with acute myeloid leukemia." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119831, (2015) (PubMed).

Rama, Dubrac, Mathivet, Ní Chárthaigh, Genet, Cristofaro, Pibouin-Fragner, Ma, Eichmann, Chédotal: "Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization." in: Nature medicine, Vol. 21, Issue 5, pp. 483-91, (2015) (PubMed).

Burke-Gaffney, Svermova, Mumby, Finney, Evans: "Raised plasma Robo4 and cardiac surgery-associated acute kidney injury." in: PLoS ONE, Vol. 9, Issue 10, pp. e111459, (2014) (PubMed).

Guijarro-Muñoz, Cuesta, Alvarez-Cienfuegos, Geng, Alvarez-Vallina, Sanz: "The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis." in: Experimental cell research, Vol. 318, Issue 4, pp. 371-8, (2012) (PubMed).

Zhang, Fisher, Newey, Smythe, Tatton, Tsaknakis, Forde, Carpenter, Athanassopoulos, Hale, Ferguson, Tyler, Watt: "The impact of proliferative potential of umbilical cord-derived endothelial progenitor cells and hypoxia on vascular tubule formation in vitro." in: Stem cells and development, Vol. 18, Issue 2, pp. 359-75, (2009) (PubMed).

Synonyms and alternative names related to ROBO4

roundabout guidance receptor 4 (ROBO4), roundabout guidance receptor 4 (Robo4), roundabout, axon guidance receptor, homolog 4 (Drosophila) (robo4), 1200012D01Rik, AI593217, ECSM4, MRB, sc:d0823, wu:fa16f09

Protein level used designations for ROBO4

  • roundabout homolog 4
  • roundabout homolog 4, magic roundabout
  • Magic roundabout
  • magic roundabout
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