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ROBO2 Products

(Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2))

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This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured ROBO2 Categories

ROBO2 Antibodies

High quality antibodies with extensive validation data.

ROBO2 ELISA Kits

Reliable ELISA kits for a wide range of species.

ROBO2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ROBO2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7168444
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN519831
Quantity 100 μg
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6747098
Quantity 100 μL
Datasheet Datasheet

Recommended ROBO2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884365
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384941
Quantity 96 tests
Datasheet Datasheet

Recommended ROBO2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318427
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7317921
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2731060
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our ROBO2 products

Gorla, Santiago, Chaudhari, Layman, Oliver, Bashaw: "Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord." in: Cell reports, Vol. 26, Issue 12, pp. 3298-3312.e4, (2019) (PubMed).

Xie, Tsai, Tsai: "COUP-TFII regulates satellite cell function and muscular dystrophy." in: The Journal of clinical investigation, Vol. 126, Issue 10, pp. 3929-3941, (2016) (PubMed).

Fan, Yang, Kumar, Tumelty, Pisarek-Horowitz, Rasouly, Sharma, Chan, Tyminski, Shamashkin, Belghasem, Henderson, Coyle, Salant, Berasi, Lu: "SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion." in: JCI insight, Vol. 1, Issue 19, pp. e86934, (2016) (PubMed).

Sanz-Pamplona, Berenguer, Cordero, Molleví, Crous-Bou, Sole, Paré-Brunet, Guino, Salazar, Santos, de Oca, Sanjuan, Rodriguez-Moranta, Moreno: "Aberrant gene expression in mucosa adjacent to tumor reveals a molecular crosstalk in colon cancer." in: Molecular cancer, Vol. 13, pp. 46, (2014) (PubMed).

Guijarro-Muñoz, Cuesta, Alvarez-Cienfuegos, Geng, Alvarez-Vallina, Sanz: "The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis." in: Experimental cell research, Vol. 318, Issue 4, pp. 371-8, (2012) (PubMed).

Geutskens, Hordijk, van Hennik: "The chemorepellent Slit3 promotes monocyte migration." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 12, pp. 7691-8, (2010) (PubMed).

Takeuchi, Inokuchi, Aoki, Suto, Tsuboi, Matsuda, Suzuki, Aiba, Serizawa, Yoshihara, Fujisawa, Sakano: "Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb." in: Cell, Vol. 141, Issue 6, pp. 1056-67, (2010) (PubMed).

Reeber, Sakai, Nakada, Dumas, Dobrenis, Johnson, Kaprielian: "Manipulating Robo expression in vivo perturbs commissural axon pathfinding in the chick spinal cord." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 35, pp. 8698-708, (2008) (PubMed).

Andrews, Barber, Hernadez-Miranda, Xian, Rakic, Sundaresan, Rabbitts, Pannell, Rabbitts, Thompson, Erskine, Murakami, Parnavelas: "The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons." in: Developmental biology, Vol. 313, Issue 2, pp. 648-58, (2008) (PubMed).

Nguyen-Ba-Charvet, Di Meglio, Fouquet, Chédotal: "Robos and slits control the pathfinding and targeting of mouse olfactory sensory axons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 16, pp. 4244-9, (2008) (PubMed).

Synonyms and alternative names related to ROBO2

roundabout guidance receptor 2 (ROBO2), roundabout guidance receptor 2 (Robo2), roundabout guidance receptor 2 (robo2), roundabout 2 (robo2), roundabout, axon guidance receptor, homolog 2 (Drosophila) (robo2), roundabout guidance receptor 2 S homeolog (robo2.S), roundabout, axon guidance receptor, homolog 2 (Drosophila) (ROBO2), 2600013A04Rik, 9430089E08Rik, anon-EST:Liang-1.75, BB097918, CG5481, CG5574, CG14347, CG14348, clone 1.75, CT17326, D-Robo2, D-robo2, D230004I22Rik, Dmel\\CG5481, dRobo-2, fus4, mKIAA1568, Robo-2, robo-2, ROBO2, Robo 2, Robo2, robo2, SAX3, sax3, unp1881

Protein level used designations for ROBO2

  • roundabout homolog 2
  • roundabout 2 precursor
  • Roundabout2 protein
  • roundabout, axon guidance receptor, homolog 2 (Drosophila)
  • roundabout, axon guidance receptor, homolog 2
  • roundabout homolog 2-like
  • CG5481-PA
  • CG5481-PB
  • Robo2
  • Roundabout2
  • SGP cluster fusion defects 4
  • lea-PA
  • lea-PB
  • roundabout 2
  • ast
  • astray
  • zmp:0000000549
  • Robo 2
  • roundabout-2
  • LOW QUALITY PROTEIN: roundabout homolog 2
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