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RNGTT Products

(RNA Guanylyltransferase and 5'-Phosphatase (RNGTT))
Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.

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Featured RNGTT Categories

RNGTT Antibodies

High quality antibodies with extensive validation data.

RNGTT ELISA Kits

Reliable ELISA kits for a wide range of species.

RNGTT Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RNGTT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7160269
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN6147053
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7306618
Quantity 100 μL
Datasheet Datasheet

Recommended RNGTT ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1143233
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1143234
Quantity 96 tests
Datasheet Datasheet

Recommended RNGTT Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318403
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2131588
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3083394
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RNGTT products

Trotman, Agana, Giltmier, Wysocki, Schoenberg: "RNA-binding proteins and heat-shock protein 90 are constituents of the cytoplasmic capping enzyme interactome." in: The Journal of biological chemistry, Vol. 293, Issue 43, pp. 16596-16607, (2018) (PubMed).

Housden, Valvezan, Kelley, Sopko, Hu, Roesel, Lin, Buckner, Tao, Yilmazel, Mohr, Manning, Perrimon: "Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi." in: Science signaling, Vol. 8, Issue 393, pp. rs9, (2015) (PubMed).

Mukherjee, Bakthavachalu, Schoenberg: "The cytoplasmic capping complex assembles on adapter protein nck1 bound to the proline-rich C-terminus of Mammalian capping enzyme." in: PLoS biology, Vol. 12, Issue 8, pp. e1001933, (2014) (PubMed).

Synonyms and alternative names related to RNGTT

RNA guanylyltransferase and 5'-phosphatase (rngtt.S), RNA guanylyltransferase and 5'-phosphatase (rngtt), RNA guanylyltransferase and 5'-phosphatase (RNGTT), mRNA-capping enzyme (LOC100439097), RNA guanylyltransferase and 5'-phosphatase (Rngtt), AU020997, CAP1A, hCAP, HCE, HCE1, MGC75787, xcap1b, zgc:76886

Protein level used designations for RNGTT

  • mRNA capping enzyme
  • RNA guanylyltransferase and 5'-phosphatase
  • mRNA-capping enzyme
  • mRNA-capping enzyme-like
  • HCAP1
  • HCE
  • MCE1
  • capping enzyme
  • RNA guanylyltransferase and 5-phosphatase
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