RNF216 Products
(Ring Finger Protein 216 (RNF216))
Categories
This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008].
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Featured RNF216 Categories
RNF216 Antibodies
High quality antibodies with extensive validation data.
Recommended RNF216 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
IHC (p)
Validations
- (1)
Cat. No.
ABIN388833
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN501040
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN357474
Quantity
0.4 mL
Datasheet
Datasheet
Recommended RNF216 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124914
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095079
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3134535
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RNF216 products
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).: "TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression." in: Molecular interventions, Vol. 3, Issue 8, pp. 466-77, (2004) (PubMed).
: "Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors." in: Nature immunology, Vol. 5, Issue 5, pp. 495-502, (2004) (PubMed).
: "ARMER, apoptotic regulator in the membrane of the endoplasmic reticulum, a novel inhibitor of apoptosis." in: Molecular cancer research : MCR, Vol. 1, Issue 7, pp. 508-18, (2003) (PubMed).
: "SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling." in: Nature immunology, Vol. 4, Issue 9, pp. 920-7, (2003) (PubMed).
: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, (2003) (PubMed).
: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
: "A novel zinc finger protein interacts with receptor-interacting protein (RIP) and inhibits tumor necrosis factor (TNF)- and IL1-induced NF-kappa B activation." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15985-91, (2002) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of Toll-like receptor 4 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 11, pp. 6633-9, (2001) (PubMed).
Synonyms and alternative names related to RNF216
ring finger protein 216 (Rnf216), ring finger protein 216 (RNF216), ring finger protein 216 (rnf216), 2810055g22rik, 2810055G22Rik, AI647468, AU019462, C86502, CAHH, F830018F18Rik, MGC147026, RGD1565135, RNF216, TRIAD3, triad3, u7i1, U7I1, ubce7ip1, Ubce7ip1, UBCE7IP1, UIP83, zin, ZINProtein level used designations for RNF216
- E3 ubiquitin-protein ligase RNF216
- ring finger protein 216
- TRIAD3 protein
- E3 ubiquitin ligase
- triad domain-containing protein 3
- ubcM4-interacting protein 83
- ubiquitin-conjugating enzyme 7-interacting protein 1
- zinc finger protein inhibiting NF-kappa-B
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