RNF2 Products
(Ring Finger Protein 2 (RNF2))
Categories
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq, Jul 2008].
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Featured RNF2 Categories
RNF2 Antibodies
High quality antibodies with extensive validation data.
RNF2 ELISA Kits
Reliable ELISA kits for a wide range of species.
RNF2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RNF2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (3)
- (6)
Cat. No.
ABIN562662
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (9)
Cat. No.
ABIN519808
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP, ChIP
Validations
- (8)
Cat. No.
ABIN6147029
Quantity
100 μL
Datasheet
Datasheet
Recommended RNF2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207349
Quantity
96 tests
Datasheet
Datasheet
Recommended RNF2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318331
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318329
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2731042
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our RNF2 products
: "Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells." in: Oncotarget, Vol. 7, Issue 10, pp. 11424-33, (2016) (PubMed).: "The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing." in: Genes & development, Vol. 29, Issue 12, pp. 1224-38, (2015) (PubMed).
: "YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment." in: Nucleic acids research, Vol. 42, Issue 4, pp. 2208-23, (2014) (PubMed).
: "TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein." in: Nature, Vol. 516, Issue 7529, pp. 116-20, (2014) (PubMed).
: "Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4." in: Molecular and cellular biology, Vol. 33, Issue 4, pp. 644-60, (2013) (PubMed).
: "Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program." in: The Journal of biological chemistry, Vol. 288, Issue 9, pp. 6238-47, (2013) (PubMed).
: "Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks." in: PLoS genetics, Vol. 9, Issue 7, pp. e1003588, (2013) (PubMed).
: "Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development." in: Genes & development, Vol. 26, Issue 13, pp. 1445-58, (2012) (PubMed).
: "Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 24, pp. 10783-90, (2010) (PubMed).
: "Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 30, pp. 10396-401, (2008) (PubMed).
Synonyms and alternative names related to RNF2
ring finger protein 2 (RNF2), ring finger protein 2 (Rnf2), ring finger protein 2 (rnf2), ring finger protein 2 L homeolog (rnf2.L), AI326319, AI450156, AU019207, BAP-1, bap-1, BAP1, bap1, DING, dinG, ding, fa19h05, HIPI3, hipi3, RING1B, Ring1B, ring1b, RING2, ring2, wu:fa19h05, wz4556Protein level used designations for RNF2
- E3 ubiquitin-protein ligase RING2
- HIP2-interacting protein 3
- RING finger protein 1B
- RING finger protein BAP-1
- huntingtin-interacting protein 2-interacting protein 3
- protein DinG
- RING1b
- ring finger protein 1b
- wz4566
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