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RNF125 Products

(Ring Finger Protein 125 (RNF125))

Categories

This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012].

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Featured RNF125 Categories

RNF125 Antibodies

High quality antibodies with extensive validation data.

RNF125 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RNF125 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN527265
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7151129
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, FACS
Validations
  • (2)
Cat. No. ABIN185241
Quantity 100 μg
Datasheet Datasheet

Recommended RNF125 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207366
Quantity 96 tests
Datasheet Datasheet

Recommended RNF125 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318218
Quantity 10 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source Yeast
Validations
Cat. No. ABIN1640486
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RNF125 products

Kim, Frederick, Levesque, Cooper, Feng, Krepler, Brill, Samuels, Hayward, Perlina, Piris, Zhang, Halaban, Herlyn, Brown, Wargo, Dummer, Flaherty, Ronai: "Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation." in: Cell reports, Vol. 11, Issue 9, pp. 1458-73, (2015) (PubMed).

Chu, Pardo, Zhao, Li, Pali, Shen, Qu, Yu, Huang, Yu, Masuda, Molineaux, Kolbinger, Aversa, de Vries, Payan, Liao: "Systematic identification of regulatory proteins critical for T-cell activation." in: Journal of biology, Vol. 2, Issue 3, pp. 21, (2004) (PubMed).

Synonyms and alternative names related to RNF125

ring finger protein 125 (RNF125), ring finger protein 125 (Rnf125), 4930553F04Rik, TRAC-1, TRAC1

Protein level used designations for RNF125

  • E3 ubiquitin-protein ligase RNF125
  • T-cell RING activation protein 1
  • T-cell ring protein identified in activation screen
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