RNASE1 Products
(Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1))
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This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
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Featured RNASE1 Categories
RNASE1 Antibodies
High quality antibodies with extensive validation data.
RNASE1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RNASE1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RNASE1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7438874
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ICC, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN2856141
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (4)
Cat. No.
ABIN1078491
Quantity
100 μL
Datasheet
Datasheet
Recommended RNASE1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959179
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959180
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959178
Quantity
96 tests
Datasheet
Datasheet
Recommended RNASE1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318142
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318140
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7389917
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our RNASE1 products
: "Multiplexed in-gel microfluidic immunoassays: characterizing protein target loss during reprobing of benzophenone-modified hydrogels." in: Scientific reports, Vol. 9, Issue 1, pp. 15389, (2019) (PubMed).: "The Human Host Defense Ribonucleases 1, 3 and 7 Are Elevated in Patients with Sepsis after Major Surgery--A Pilot Study." in: International journal of molecular sciences, Vol. 17, Issue 3, pp. 294, (2016) (PubMed).
: "Integrated Microfluidic Lectin Barcode Platform for High-Performance Focused Glycomic Profiling." in: Scientific reports, Vol. 6, pp. 20297, (2016) (PubMed).
: "Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125596, (2015) (PubMed).
: "Interplay of LRRK2 with chaperone-mediated autophagy." in: Nature neuroscience, Vol. 16, Issue 4, pp. 394-406, (2013) (PubMed).
: "It takes two to flirt with a dimeric RNase." in: Biopolymers, Vol. 91, Issue 12, pp. 989-94, (2009) (PubMed).
: "The solution structure and dynamics of human pancreatic ribonuclease determined by NMR spectroscopy provide insight into its remarkable biological activities and inhibition." in: Journal of molecular biology, Vol. 379, Issue 5, pp. 953-65, (2008) (PubMed).
: "DNA variation in MSR1, RNASEL and E-cadherin genes and prostate cancer in Poland." in: Urologia internationalis, Vol. 79, Issue 1, pp. 44-9, (2007) (PubMed).
: "A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity toward malignant cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 14, pp. 7768-73, (1999) (PubMed).
Synonyms and alternative names related to RNASE1
ribonuclease A family member 1, pancreatic (RNASE1), ribonuclease pancreatic-like (LOC475395), ribonuclease A family member k6 (RNASE6), Ribonuclease 1 (Rnase1), ribonuclease 1 (RNS1), ribonuclease, RNase A family, 1 (pancreatic) (RNASE1), ribonuclease, RNase A family, 1 (pancreatic) (Rnase1), ribonuclease pancreatic (LOC101113761), AI574248, ATRNS1, Rib-1, RIB1, Rib1, RIBONUCLEASE 1, ribonuclease 1, RNASE1, RNS1, SRN, T17M13.16, T17M13_16Protein level used designations for RNASE1
- ribonuclease pancreatic
- ribonuclease, RNase A family, 1 (pancreatic)
- ribonuclease pancreatic-like
- RNase 1
- RNase A
- Ribonuclease pancreatic
- pancreatic ribonuclease
- angiogenin
- leukocyte ribonuclease A-1
- ribonuclease A
- ribonuclease A/angiogenin
- ribonuclease A (pancreatic)
- HP-RNase
- RIB-1
- RNase upI-1
- ribonuclease 1
- ribonuclease 1, pancreatic
- RL1
- RNase 1 gamma
- ribonuclease 1 pancreatic
- ribonuclease RNase A family 1
- ribonuclease pancreatic beta-type
- S-RNase
- ribonuclease BS-1
- seminal RNase
- seminal ribonuclease
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