Ring Finger Protein 8 Products
(Ring Finger Protein 8 (RNF8))
Categories
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
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Featured Ring Finger Protein 8 Categories
Ring Finger Protein 8 Antibodies
High quality antibodies with extensive validation data.
Ring Finger Protein 8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Ring Finger Protein 8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (4)
Cat. No.
ABIN184931
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
- (3)
Cat. No.
ABIN522468
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow, Human, Mouse, Rat, Xenopus laevis
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN925946
Quantity
100 μg
Datasheet
Datasheet
Recommended Ring Finger Protein 8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207377
Quantity
96 tests
Datasheet
Datasheet
Recommended Ring Finger Protein 8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
Cat. No.
ABIN1318397
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095050
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136693
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Ring Finger Protein 8 products
: "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9396-410, (2016) (PubMed).: "Epstein-Barr virus BZLF1 protein impairs accumulation of host DNA damage proteins at damage sites in response to DNA damage." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 8, pp. 937-50, (2015) (PubMed).
: "Role of ATM in the formation of the replication compartment during lytic replication of Epstein-Barr virus in nasopharyngeal epithelial cells." in: Journal of virology, Vol. 89, Issue 1, pp. 652-68, (2014) (PubMed).
: "Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 3, pp. 1029-34, (2013) (PubMed).
: "Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage." in: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 2941-50, (2013) (PubMed).
: "Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1." in: Nature, Vol. 466, Issue 7309, pp. 941-6, (2010) (PubMed).
: "The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress." in: Nature, Vol. 462, Issue 7275, pp. 886-90, (2009) (PubMed).
: "N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8." in: European journal of biochemistry / FEBS, Vol. 268, Issue 9, pp. 2725-32, (2001) (PubMed).
Synonyms and alternative names related to Ring Finger Protein 8
ring finger protein 8 (RNF8), ring finger protein 8 (Rnf8), ring finger protein 8, E3 ubiquitin protein ligase S homeolog (rnf8.S), ring finger protein 8, E3 ubiquitin protein ligase L homeolog (rnf8.L), ring finger protein 8, E3 ubiquitin protein ligase (rnf8), 3830404E21Rik, AIP37, fc66f09, hRNF8, RNF8, rnf8, wu:fc66f09, zgc:55936, zgc:77313Protein level used designations for Ring Finger Protein 8
- C3HC4-type zinc finger protein
- E3 ubiquitin-protein ligase RNF8
- UBC13/UEV-interacting ring finger protein
- ring finger protein (C3HC4 type) 8
- ActA binding protein 2
- actA-interacting protein 37
- laXp180
- E3 ubiquitin-protein ligase RNF8 A
- E3 ubiquitin-protein ligase RNF8-A
- RING finger protein 8 A
- RING finger protein 8-A
- E3 ubiquitin-protein ligase RNF8 B
- E3 ubiquitin-protein ligase RNF8-B
- RING finger protein 8 B
- RING finger protein 8-B
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