RIN2 Products
(Ras and Rab Interactor 2 (RIN2))
Categories
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011].
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Featured RIN2 Categories
RIN2 Antibodies
High quality antibodies with extensive validation data.
RIN2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RIN2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN565735
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN527065
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN565734
Quantity
50 μL
Datasheet
Datasheet
Recommended RIN2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318085
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095019
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3137102
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RIN2 products
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).: "The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling." in: Cell research, Vol. 22, Issue 10, pp. 1479-501, (2012) (PubMed).
Synonyms and alternative names related to RIN2
Ras and Rab interactor 2 (Rin2), Ras and Rab interactor 2 (RIN2), Ras and Rab interactor 2 (rin2), 2010003K16Rik, 4632403N06Rik, AW821980, MACS, rassf4, RASSF4, RIN2, RINLProtein level used designations for RIN2
- ras and Rab interactor 2
- Ras and Rab interactor 2
- RAB5 interacting protein 2
- ras and Rab interactor 2-like
- RAS association (RalGDS/AF-6) domain containing protein JC265
- RAS association domain family 4
- RAS inhibitor JC265
- RAS interaction/interference protein 2
- ras interaction/interference protein 2
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