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Rhotekin Products

(Rhotekin (RTKN))

Categories

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured Rhotekin Categories

Rhotekin Antibodies

High quality antibodies with extensive validation data.

Rhotekin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Rhotekin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (8)
Cat. No. ABIN1500702
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN562746
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7168074
Quantity 100 μL
Datasheet Datasheet

Recommended Rhotekin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6209037
Quantity 96 tests
Datasheet Datasheet

Recommended Rhotekin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318954
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419691
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424701
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Rhotekin products

Pusapati, Eiseler, Rykx, Vandoninck, Derua, Waelkens, Van Lint, von Wichert, Seufferlein: "Protein kinase D regulates RhoA activity via rhotekin phosphorylation." in: The Journal of biological chemistry, Vol. 287, Issue 12, pp. 9473-83, (2012) (PubMed).

Synonyms and alternative names related to Rhotekin

rhotekin (RTKN), rhotekin (rtkn), rhotekin (Rtkn), RTKN

Protein level used designations for Rhotekin

  • rhotekin
  • rhotekin-like
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