RHOC Products
(Ras Homolog Gene Family, Member C (RHOC))
Categories
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
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Featured RHOC Categories
RHOC Antibodies
High quality antibodies with extensive validation data.
RHOC ELISA Kits
Reliable ELISA kits for a wide range of species.
RHOC Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RHOC Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN513475
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (5)
Cat. No.
ABIN513476
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (4)
Cat. No.
ABIN2854791
Quantity
100 μL
Datasheet
Datasheet
Recommended RHOC ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969837
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1155612
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1155615
Quantity
96 tests
Datasheet
Datasheet
Recommended RHOC Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1318024
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124787
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7491411
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our RHOC products
: "Transcription of HOTAIR is regulated by RhoC-MRTF-A-SRF signaling pathway in human breast cancer cells." in: Cellular signalling, Vol. 31, pp. 87-95, (2017) (PubMed).: "Knockdown of RHOC by shRNA suppresses invasion and migration of cholangiocellular carcinoma cells via inhibition of MMP2, MMP3, MMP9 and epithelial-mesenchymal transition." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 5255-61, (2017) (PubMed).
: "RhoB/ROCK mediates oxygen-glucose deprivation-stimulated syncytiotrophoblast microparticle shedding in preeclampsia." in: Cell and tissue research, Vol. 366, Issue 2, pp. 411-425, (2016) (PubMed).
: "Rhos and Rho kinases in the rat prostate: their possible functional roles and distributions." in: Molecular and cellular biochemistry, Vol. 358, Issue 1-2, pp. 207-13, (2011) (PubMed).
: "Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation." in: Endocrinology, Vol. 151, Issue 4, pp. 1732-42, (2010) (PubMed).
: "Rho GTPases modulate entry of Ebola virus and vesicular stomatitis virus pseudotyped vectors." in: Journal of virology, Vol. 83, Issue 19, pp. 10176-86, (2009) (PubMed).
: "Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets." in: BMC cancer, Vol. 8, pp. 19, (2008) (PubMed).
: "Flow cytometry for real-time measurement of guanine nucleotide binding and exchange by Ras-like GTPases." in: Analytical biochemistry, Vol. 381, Issue 2, pp. 258-66, (2008) (PubMed).
Synonyms and alternative names related to RHOC
ras homolog family member C L homeolog (rhoc.L), ras homolog family member C (RHOC), ras homolog family member C (rhoc), ras homolog family member C (Rhoc), AI324259, ARH9, Arh9, ARHC, Arhc, CRHOC, H9, LOC100221682, RHOH9Protein level used designations for RHOC
- ras homolog gene family, member C
- rho-related GTP-binding protein RhoC
- RAS-related homolog 9
- oncogene RHO H9
- rho cDNA clone 9
- rhoC GTPase
- small GTP binding protein RhoC
- SIG-61
- aplysia ras-related homolog 9 (RhoC)
- ras homolog 9 (RhoC)
- silica-induced gene 61 protein
- GTP-binding protein
- GTPase cRhoC
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