RGS14 Products
(Regulator of G-Protein Signaling 14 (RGS14))
Categories
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
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Featured RGS14 Categories
RGS14 Antibodies
High quality antibodies with extensive validation data.
RGS14 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RGS14 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IF
Validations
- (3)
Cat. No.
ABIN524067
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6258314
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN2856368
Quantity
100 μL
Datasheet
Datasheet
Recommended RGS14 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6221040
Quantity
96 tests
Datasheet
Datasheet
Recommended RGS14 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317939
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317937
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124814
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our RGS14 products
: "Mossy fiber sprouting into the hippocampal region CA2 in patients with temporal lobe epilepsy." in: Hippocampus, Vol. 31, Issue 6, pp. 580-592, (2021) (PubMed).: "Novel connection between newborn granule neurons and the hippocampal CA2 field." in: Experimental neurology, Vol. 263, pp. 285-92, (2014) (PubMed).
: "Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain." in: The Journal of comparative neurology, Vol. 522, Issue 1, pp. 186-203, (2014) (PubMed).
: "Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits." in: Nature neuroscience, Vol. 17, Issue 2, pp. 269-79, (2014) (PubMed).
: "The hippocampal CA2 region is essential for social memory." in: Nature, Vol. 508, Issue 7494, pp. 88-92, (2014) (PubMed).
: "Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by G?i1 and G?i-linked G protein-coupled receptors." in: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 3620-31, (2013) (PubMed).
: "Delta-opioid receptors mediate unique plasticity onto parvalbumin-expressing interneurons in area CA2 of the hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 36, pp. 14567-78, (2013) (PubMed).
: "Activation of the regulator of G protein signaling 14-G?i1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A." in: Biochemistry, Vol. 50, Issue 5, pp. 752-62, (2011) (PubMed).
: "RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 39, pp. 16994-8, (2010) (PubMed).
: "Molecular cloning and expression analysis of rat Rgs12 and Rgs14." in: Biochemical and biophysical research communications, Vol. 233, Issue 3, pp. 770-7, (1997) (PubMed).
Synonyms and alternative names related to RGS14
regulator of G protein signaling 14 (RGS14), regulator of G-protein signaling 14 (Rgs14), regulator of G-protein signaling 14 L homeolog (rgs14.L), regulator of G-protein signaling 14 (RGS14), regulator of G-protein signalling 14 (rgs14), regulator of G protein signaling 14 (Rgs14), regulator of G protein signaling 14a (rgs14a), MGC80558, RGS14, rgs14, RPIP1, wu:fi04g12Protein level used designations for RGS14
- regulator of G-protein signalling 14
- RAP1/RAP2-interacting protein
- rap1/rap2 interacting protein
- regulator of G-protein signaling 14
- Regulator of G-protein signaling 14
- regulator of G-protein signaling 14-like
- LOW QUALITY PROTEIN: regulator of G-protein signaling 14
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