RFX1 Products
(Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))
Categories
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. [provided by RefSeq, Jul 2008].
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Featured RFX1 Categories
RFX1 Antibodies
High quality antibodies with extensive validation data.
RFX1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RFX1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7159682
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN1537643
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Mouse, Pig, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6744549
Quantity
100 μL
Datasheet
Datasheet
Recommended RFX1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317876
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094950
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3134194
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RFX1 products
: "RFX1 and RFX3 Transcription Factors Interact with the D Sequence of Adeno-Associated Virus Inverted Terminal Repeat and Regulate AAV Transduction." in: Scientific reports, Vol. 8, Issue 1, pp. 210, (2018) (PubMed).: "Dynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation." in: Scientific reports, Vol. 6, pp. 19069, (2016) (PubMed).
: "RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells." in: Oncotarget, Vol. 5, Issue 13, pp. 4909-19, (2014) (PubMed).
: "RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells." in: Carcinogenesis, Vol. 35, Issue 12, pp. 2807-14, (2014) (PubMed).
: "SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma." in: Neoplasia (New York, N.Y.), Vol. 16, Issue 7, pp. 595-605, (2014) (PubMed).
Synonyms and alternative names related to RFX1
regulatory factor X1 (RFX1), regulatory factor X, 1 (influences HLA class II expression) (Rfx1), regulatory factor X1 (Rfx1), regulatory factor X, 1a (influences HLA class II expression) (rfx1a), AI047719, AI385641, EFC, RFX, zgc:162914Protein level used designations for RFX1
- MHC class II regulatory factor RFX
- MHC class II regulatory factor RFX1
- enhancer factor C
- regulatory factor X 1
- trans-acting regulatory factor 1
- transcription factor RFX1
- vregulatory factor X, 1 (influences HLA class II expression)
- regulatory factor X1
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