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RFX1 Products

(Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

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This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. [provided by RefSeq, Jul 2008].

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Featured RFX1 Categories

RFX1 Antibodies

High quality antibodies with extensive validation data.

RFX1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RFX1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7159682
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN1537643
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Mouse, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6744549
Quantity 100 μL
Datasheet Datasheet

Recommended RFX1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317876
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094950
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134194
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RFX1 products

Julien, Chassagne, Peccate, Lorain, Piétri-Rouxel, Danos, Benkhelifa-Ziyyat: "RFX1 and RFX3 Transcription Factors Interact with the D Sequence of Adeno-Associated Virus Inverted Terminal Repeat and Regulate AAV Transduction." in: Scientific reports, Vol. 8, Issue 1, pp. 210, (2018) (PubMed).

Zhu, Li, Yang, Tian, Wang, Yuan, Dong, He, Wang, Li: "Dynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation." in: Scientific reports, Vol. 6, pp. 19069, (2016) (PubMed).

Su, Tseng, Hsu, Tai, Huang, Ko, Lin, Liu, Chen, Shiau: "RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells." in: Oncotarget, Vol. 5, Issue 13, pp. 4909-19, (2014) (PubMed).

Su, Chiang, Tseng, Tai, Hsu, Li, Huang, Ko, Lin, Chu, Liu, Chen, Shiau: "RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells." in: Carcinogenesis, Vol. 35, Issue 12, pp. 2807-14, (2014) (PubMed).

Su, Tseng, Wu, Hsu, Tai, Li, Chen, Liu, Chen, Shiau: "SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma." in: Neoplasia (New York, N.Y.), Vol. 16, Issue 7, pp. 595-605, (2014) (PubMed).

Synonyms and alternative names related to RFX1

regulatory factor X1 (RFX1), regulatory factor X, 1 (influences HLA class II expression) (Rfx1), regulatory factor X1 (Rfx1), regulatory factor X, 1a (influences HLA class II expression) (rfx1a), AI047719, AI385641, EFC, RFX, zgc:162914

Protein level used designations for RFX1

  • MHC class II regulatory factor RFX
  • MHC class II regulatory factor RFX1
  • enhancer factor C
  • regulatory factor X 1
  • trans-acting regulatory factor 1
  • transcription factor RFX1
  • vregulatory factor X, 1 (influences HLA class II expression)
  • regulatory factor X1
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