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RFWD3 Products

(Ring Finger and WD Repeat Domain 3 (RFWD3))

Categories

E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.

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Featured RFWD3 Categories

RFWD3 Antibodies

High quality antibodies with extensive validation data.

RFWD3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RFWD3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6257465
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7187949
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN565828
Quantity 100 μg
Datasheet Datasheet

Recommended RFWD3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207368
Quantity 96 tests
Datasheet Datasheet

Recommended RFWD3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317874
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094992
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136488
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to RFWD3

ring finger and WD repeat domain 3 (Rfwd3), ring finger and WD repeat domain 3 (RFWD3), BC027246, RFWD3, RGD1305243, RNF201

Protein level used designations for RFWD3

  • ring finger and WD repeat domain 3
  • RING finger and WD repeat domain-containing protein 3-like
  • E3 ubiquitin-protein ligase RFWD3
  • RING finger and WD repeat domain-containing protein 3
  • RING finger protein 201
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