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RFWD2 Proteins

(Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2))

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in JUN ubiquitination and degradation. Directly involved in p53 (TP53) ubiquitination and degradation, thereby abolishing p53-dependent transcription and apoptosis. Ubiquitinates p53 independently of MDM2 or RCHY1. Probably mediates E3 ubiquitin ligase activity by functioning as the essential RING domain subunit of larger E3 complexes. In contrast, it does not constitute the catalytic RING subunit in the DCX DET1-COP1 complex that negatively regulates JUN, the ubiquitin ligase activity being mediated by RBX1 (By similarity).

recommended

RFWD2 Protein (AA 632-731) (GST tag) (ABIN1317872)

RFWD2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

RFWD2 Protein (AA 1-731) (Strep Tag) (ABIN3095004)

RFWD2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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recommended

RFWD2 Protein (AA 1-733) (Strep Tag) (ABIN3137447)

RFWD2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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RFWD2 Proteins by Origin

Find RFWD2 Proteins for a variety of species such as anti-Human RFWD2, anti-Mouse RFWD2. The species listed below are among those available. Click on a link to go to the corresponding products.

RFWD2 Proteins by Source

Here you will find RFWD2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

RFWD2 Proteins by Protein Type

Here you can find RFWD2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

RFWD2 Proteins by Application

Find RFWD2 Proteins validated for a specific application such as ELISA, WB, AbP, SDS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular RFWD2 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

RFWD2 Protein (AA 632-731) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1317872

Quantity 10 μg

Datasheet Datasheet

RFWD2 Protein (AA 1-731) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3095004

Quantity 1 mg

Datasheet Datasheet

RFWD2 Protein (AA 1-733) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3137447

Quantity 1 mg

Datasheet Datasheet

RFWD2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2730790

Quantity 20 μg

Datasheet Datasheet

RFWD2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2730791

Quantity 20 μg

Datasheet Datasheet

Aliases for RFWD2 Proteins

ring finger and WD repeat domain 2 (RFWD2) Proteins
ring finger and WD repeat domain 2 (Rfwd2) Proteins
ring finger and WD repeat domain 2, E3 ubiquitin protein ligase (rfwd2) Proteins
ring finger and WD repeat domain 2, E3 ubiquitin protein ligase L homeolog (rfwd2.L) Proteins
ring finger and WD repeat domain 2 (rfwd2) Proteins
AI316802 Proteins
C80879 Proteins
COP1 Proteins
Cop1 Proteins
cop1 Proteins
RFWD2 Proteins
RGD1304773 Proteins
RNF200 Proteins
rnf200 Proteins
zgc:163067 Proteins

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RFWD2 Proteins by Origin

RFWD2 Proteins by Source

RFWD2 Proteins by Protein Type

RFWD2 Proteins by Application

Popular RFWD2 Proteins

Aliases for RFWD2 Proteins

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