RFFL Products
(Ring Finger and FYVE-Like Domain Containing 1 (RFFL))
Categories
Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates (By similarity). Overexpression slows protein traffic through recycling endosomes.
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Featured RFFL Categories
RFFL Antibodies
High quality antibodies with extensive validation data.
RFFL Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RFFL Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
ABIN566759
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7151117
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (5)
- (1)
Cat. No.
ABIN1881744
Quantity
400 μL
Datasheet
Datasheet
Recommended RFFL ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6221029
Quantity
96 tests
Datasheet
Datasheet
Recommended RFFL Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317849
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317851
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095003
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RFFL products
: "Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses." in: The Journal of biological chemistry, Vol. 289, Issue 27, pp. 19231-44, (2014) (PubMed).: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).
: "Common variants at ten loci influence QT interval duration in the QTGEN Study." in: Nature genetics, Vol. 41, Issue 4, pp. 399-406, (2009) (PubMed).
: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, (2009) (PubMed).
: "CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation." in: Current biology : CB, Vol. 18, Issue 9, pp. 641-9, (2008) (PubMed).
: "CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 5, pp. 670-82, (2008) (PubMed).
: "Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 16, pp. 6170-5, (2004) (PubMed).
: "Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment." in: Molecular biology of the cell, Vol. 15, Issue 10, pp. 4444-56, (2004) (PubMed).
: "Crystal structure of a FYVE-type zinc finger domain from the caspase regulator CARP2." in: Structure (London, England : 1993), Vol. 12, Issue 12, pp. 2257-63, (2004) (PubMed).
Synonyms and alternative names related to RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase (RFFL), ring finger and FYVE-like domain containing E3 ubiquitin protein ligase L homeolog (rffl.L), ring finger and FYVE-like domain containing 1 (Rffl), ring finger and FYVE like domain containing protein (Rffl), ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (Rffl), 1700051E09Rik, 4930516L10Rik, BG080975, CARP-2, Carp2, CARP2, FRING, MGC84042, RFFL, Rffl, RIFIFYLIN, RNF34L, RNF189Protein level used designations for RFFL
- E3 ubiquitin-protein ligase rififylin
- ring finger and FYVE-like domain containing 1
- rififylin
- e3 ubiquitin-protein ligase rififylin-like
- RING finger and FYVE-like domain-containing protein 1
- fring
- FYVE-RING finger protein SAKURA
- RING finger protein 189
- caspase regulator CARP2
- caspases-8 and -10-associated RING finger protein 2
- FYVE-RING finger protein Sakura
- RING finger protein SAKURA
- ring finger and FYVE like domain containing protein
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