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RFC4 Products

(Replication Factor C (Activator 1) 4, 37kDa (RFC4))

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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008].

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Featured RFC4 Categories

RFC4 Antibodies

High quality antibodies with extensive validation data.

RFC4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RFC4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7261451
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), RNAi
Validations
  • (6)
Cat. No. ABIN562635
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (7)
Cat. No. ABIN6146881
Quantity 100 μL
Datasheet Datasheet

Recommended RFC4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232216
Quantity 96 tests
Datasheet Datasheet

Recommended RFC4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317845
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317843
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3127850
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RFC4 products

Jiang, Zhang, Chen, Lei, Zhang, Wang, Jin, Lan, Zhou, Huang, Li, Liu, Gao, Xie, Zhou, Nice, Peng, Cao, Wei, Wang, Huang: "Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma." in: Autophagy, pp. 1-17, (2019) (PubMed).

Wang, Zhang, Lei, Li, Jiang, Lan, Liu, Chen, Gao, Xie, Chen, Zhu, Liu, Xie, Peng, Nice, Wu, Huang, Wei: "Identification of ANXA2 (annexin A2) as a specific bleomycin target to induce pulmonary fibrosis by impeding TFEB-mediated autophagic flux." in: Autophagy, pp. 1-14, (2017) (PubMed).

Redondo-Muñoz, Rodríguez, Silió, Pérez-García, Valpuesta, Carrera: "Phosphoinositide 3-kinase beta controls replication factor C assembly and function." in: Nucleic acids research, Vol. 41, Issue 2, pp. 855-68, (2013) (PubMed).

Collis, Schwaninger, Ntambi, Keller, Nelson, Dillehay, Deweese: "Evasion of early cellular response mechanisms following low level radiation-induced DNA damage." in: The Journal of biological chemistry, Vol. 279, Issue 48, pp. 49624-32, (2004) (PubMed).

Synonyms and alternative names related to RFC4

replication factor C subunit 4 (PFL2005w), Replication factor C subunit 4 (EHI_167150), replication factor C subunit 4 (TP03_0432), replication factor C subunit 4 (Tb11.01.1310), replication factor C subunit 4 (BBOV_IV002210), replication factor C subunit 4 (rfc4), Replication factor C subunit 4 (rfc-4), replication factor C (activator 1) 4 (Rfc4), replication factor C subunit 4 (Rfc4), replication factor C subunit 4 (RFC4), replication factor C subunit 4 L homeolog (rfc4.L), 21.m03053, 44.t00003, A1, AI894123, AU040575, rfc2, rfc4, RFC37

Protein level used designations for RFC4

  • replication factor C subunit 4
  • Replication factor C subunit 4
  • activator 1 subunit 4
  • A1 37 kDa subunit
  • RF-C 37 kDa subunit
  • RFC 37 kDa subunit
  • activator 1 37 kDa subunit
  • replication factor C 37 kDa subunit
  • replication factor C p37 subunit
  • replication factor C 4
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