RFC4 Products
(Replication Factor C (Activator 1) 4, 37kDa (RFC4))
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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008].
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Featured RFC4 Categories
RFC4 Antibodies
High quality antibodies with extensive validation data.
RFC4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RFC4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7261451
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), RNAi
Validations
- (6)
Cat. No.
ABIN562635
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (7)
Cat. No.
ABIN6146881
Quantity
100 μL
Datasheet
Datasheet
Recommended RFC4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232216
Quantity
96 tests
Datasheet
Datasheet
Recommended RFC4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317845
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317843
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3127850
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RFC4 products
: "Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma." in: Autophagy, pp. 1-17, (2019) (PubMed).: "Identification of ANXA2 (annexin A2) as a specific bleomycin target to induce pulmonary fibrosis by impeding TFEB-mediated autophagic flux." in: Autophagy, pp. 1-14, (2017) (PubMed).
: "Phosphoinositide 3-kinase beta controls replication factor C assembly and function." in: Nucleic acids research, Vol. 41, Issue 2, pp. 855-68, (2013) (PubMed).
: "Evasion of early cellular response mechanisms following low level radiation-induced DNA damage." in: The Journal of biological chemistry, Vol. 279, Issue 48, pp. 49624-32, (2004) (PubMed).
Synonyms and alternative names related to RFC4
replication factor C subunit 4 (PFL2005w), Replication factor C subunit 4 (EHI_167150), replication factor C subunit 4 (TP03_0432), replication factor C subunit 4 (Tb11.01.1310), replication factor C subunit 4 (BBOV_IV002210), replication factor C subunit 4 (rfc4), Replication factor C subunit 4 (rfc-4), replication factor C (activator 1) 4 (Rfc4), replication factor C subunit 4 (Rfc4), replication factor C subunit 4 (RFC4), replication factor C subunit 4 L homeolog (rfc4.L), 21.m03053, 44.t00003, A1, AI894123, AU040575, rfc2, rfc4, RFC37Protein level used designations for RFC4
- replication factor C subunit 4
- Replication factor C subunit 4
- activator 1 subunit 4
- A1 37 kDa subunit
- RF-C 37 kDa subunit
- RFC 37 kDa subunit
- activator 1 37 kDa subunit
- replication factor C 37 kDa subunit
- replication factor C p37 subunit
- replication factor C 4
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