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REV1 Products

(REV1, Polymerase (DNA Directed) (REV1))

Categories

This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found. [provided by RefSeq, Jul 2008].

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Featured REV1 Categories

REV1 Antibodies

High quality antibodies with extensive validation data.

REV1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended REV1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7437113
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7150293
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA, ICC, IF
Validations
  • (2)
Cat. No. ABIN6259541
Quantity 100 μL
Datasheet Datasheet

Recommended REV1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317822
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2131548
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401377
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our REV1 products

Hashimoto, Cho, Yang, Akagi, Ohashi, Tateishi, de Wind, Hanaoka, Ohmori, Moriya: "The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site." in: The Journal of biological chemistry, Vol. 287, Issue 12, pp. 9613-22, (2012) (PubMed).

Yang, Hashimoto, de Wind, Blair, Moriya: "Two distinct translesion synthesis pathways across a lipid peroxidation-derived DNA adduct in mammalian cells." in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 191-8, (2008) (PubMed).

Masuda, Takahashi, Tsunekuni, Minami, Sumii, Miyagawa, Kamiya: "Deoxycytidyl transferase activity of the human REV1 protein is closely associated with the conserved polymerase domain." in: The Journal of biological chemistry, Vol. 276, Issue 18, pp. 15051-8, (2001) (PubMed).

Synonyms and alternative names related to REV1

DNA-directed DNA polymerase (REV1), HIG1 hypoxia inducible domain family member 1C (HIGD1C), REV1, DNA directed polymerase (Rev1), REV1, DNA directed polymerase (REV1), 1110027I23Rik, ARABIDOPSIS THALIANA HOMOLOG OF REVERSIONLESS 1, ATREV1, AU022044, K23L20.9, K23L20_9, Rev1l, REV1L

Protein level used designations for REV1

  • DNA repair protein REV1
  • rev1-like terminal deoxycytidyl transferase
  • AIBP80
  • REV1 homolog
  • REV1- like
  • alpha integrin-binding protein 80
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