Retinoblastoma Binding Protein 8 Products
(Retinoblastoma Binding Protein 8 (RBBP8))
Categories
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008].
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Featured Retinoblastoma Binding Protein 8 Categories
Retinoblastoma Binding Protein 8 Antibodies
High quality antibodies with extensive validation data.
Retinoblastoma Binding Protein 8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Retinoblastoma Binding Protein 8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN604928
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7150164
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (1)
Cat. No.
ABIN2856639
Quantity
100 μL
Datasheet
Datasheet
Recommended Retinoblastoma Binding Protein 8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6203591
Quantity
96 tests
Datasheet
Datasheet
Recommended Retinoblastoma Binding Protein 8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1317559
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091883
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136083
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Retinoblastoma Binding Protein 8 products
: "ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair." in: Nucleic acids research, Vol. 46, Issue 3, pp. 1266-1279, (2018) (PubMed).: "ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks." in: Molecular cell, Vol. 68, Issue 1, pp. 61-75.e5, (2017) (PubMed).
: "Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." in: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).
: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." in: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).
: "RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 6, pp. 787-98, (2016) (PubMed).
: "MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex." in: Nature communications, Vol. 6, pp. 7744, (2015) (PubMed).
: "FANCD2 binds CtIP and regulates DNA-end resection during DNA interstrand crosslink repair." in: Cell reports, Vol. 7, Issue 4, pp. 1039-47, (2014) (PubMed).
: "Quantitation of DNA double-strand break resection intermediates in human cells." in: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).
: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." in: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).
: "SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage." in: Genes & development, Vol. 26, Issue 11, pp. 1196-208, (2012) (PubMed).
Synonyms and alternative names related to Retinoblastoma Binding Protein 8
RB binding protein 8, endonuclease (RBBP8), retinoblastoma binding protein 8, endonuclease (Rbbp8), RB binding protein 8, endonuclease (Rbbp8), retinoblastoma binding protein 8 L homeolog (rbbp8.L), retinoblastoma binding protein 8 (rbbp8), 9930104E21Rik, COM1, CTIP, CtIP, DKFZp469K0714, JWDS, RBBP-8, RBBP8, RGD1308872, RIM, SAE2, SCKL2Protein level used designations for Retinoblastoma Binding Protein 8
- CTBP-interacting protein
- DNA endonuclease RBBP8
- RBBP-8
- sporulation in the absence of SPO11 protein 2 homolog
- ctBP-interacting protein
- retinoblastoma-binding protein 8
- retinoblastoma binding protein 8
- CtBP-interacting protein
- retinoblastoma-binding protein 8-like
Did you look for something else?
- Retinoblastoma Binding Protein 4
- Retinoblastoma 1
- Retinaldehyde Binding Protein 1
- Retinal Pigment Epithelium-Specific Protein 65kDa
- Retinal Outer Segment Membrane Protein 1
- Retinal Homeobox Gene 3
- Retinal Homeobox Gene 1
- Retinal G Protein Coupled Receptor
- Retina and Anterior Neural Fold Homeobox
- Reticulum Cell
- Reticulon 4 Receptor-Like 2
- Reticulon 4
- Reticulon 3
- Reticulon 2
- Reticulon 1C
- Reticulon 1A/B
- Reticulon 1A
- Reticulon 1
- Retbindin
- Ret Proto-Oncogene
- Retinoblastoma Protein (Rb)
- Retinoic Acid
- Retinoic Acid Early Transcript 1E
- Retinoic Acid Early Transcript 1G
- Retinoic Acid Induced 12
- Retinoic Acid Receptor alpha
- Retinoic Acid Receptor beta
- Retinoic Acid Receptor, gamma
- Retinoid X Receptor beta
- Retinoid X Receptor, alpha
- Retinoid X Receptor, gamma
- Retinol Binding Protein 1, Cellular
- Retinol Binding Protein 2, Cellular
- Retinol Binding Protein 5
- Retinol Dehydrogenase 14 (All-Trans/9-Cis/11-Cis)
- Retinol Dehydrogenase 5 (11-Cis/9-Cis)
- Retinol-Binding Protein
- RETNLB
- RETNLG
- RETSAT
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