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Reticulon 4 Products

(Reticulon 4 (RTN4))
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured Reticulon 4 Categories

Reticulon 4 Antibodies

High quality antibodies with extensive validation data.

Reticulon 4 ELISA Kits

Reliable ELISA kits for a wide range of species.

Reticulon 4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Reticulon 4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Monkey
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN574094
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Pig, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN959415
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN674859
Quantity 100 μL
Datasheet Datasheet

Recommended Reticulon 4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6969915
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969916
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962625
Quantity 96 tests
Datasheet Datasheet

Recommended Reticulon 4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275359
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275357
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275360
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Reticulon 4 products

Jin, Hu, Liu, Rana, Aguilera-Barrantes, Kong, Kumar, Wang, Gao, Wang, Duan, Shi, Song, Yang, Li, Han, Zhao, Fan, Miao: "Nogo-B receptor increases the resistance of estrogen receptor positive breast cancer to paclitaxel." in: Cancer letters, Vol. 419, pp. 233-244, (2019) (PubMed).

Farías, Fréal, Tortosa, Stucchi, Pan, Portegies, Will, Altelaar, Hoogenraad: "Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity." in: Neuron, Vol. 102, Issue 1, pp. 184-201.e8, (2019) (PubMed).

Chino, Hatta, Natsume, Mizushima: "Intrinsically Disordered Protein TEX264 Mediates ER-phagy." in: Molecular cell, Vol. 74, Issue 5, pp. 909-921.e6, (2019) (PubMed).

Zhang, Yu, Guo, Yang, Chen, Ma, Li, Wei, Li, Wang, Hu, Zhang, Kong, Miao, Hu, Hajjar, Zhu, Han, Duan: "Rosiglitazone alleviates α-naphthylisothiocyanate-induced intrahepatic cholestasis in mice - The role of circulating 15d-PGJ2 and Nogo." in: British journal of pharmacology, (2019) (PubMed).

Koper, Kamińska, Milewska, Sawicki, Mariak, Kemona, Matowicka-Karna: "The isoform A of reticulon-4 (Nogo-A) in cerebrospinal fluid of primary brain tumor patients: influencing factors." in: Oncotarget, Vol. 9, Issue 38, pp. 25048-25056, (2018) (PubMed).

Gao, Wang, Jin, Hu, Duan, Shi, Du, Song, Yang, Li, Han, Zhao, Zhang, Fan, Miao: "Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells." in: Breast cancer research : BCR, Vol. 20, Issue 1, pp. 112, (2018) (PubMed).

Kawaguchi, Tashiro, Taniguchi, Kawai, Tanaka, Okuda, Hayashi, Uchiyama: "Nogo-B (Reticulon-4B) functions as a negative regulator of the apoptotic pathway through the interaction with c-FLIP in colorectal cancer cells." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1864, Issue 8, pp. 2600-2609, (2018) (PubMed).

Rodríguez-Feo, Gallego-Delgado, Puerto, Wandosell, Osende: "Reticulon-4B/Nogo-B acts as a molecular linker between microtubules and actin cytoskeleton in vascular smooth muscle cells." in: Biochimica et biophysica acta, Vol. 1863, Issue 8, pp. 1985-95, (2016) (PubMed).

Feng, Hao, Yang, Qu, Zheng, Liang, Jin et al.: "Transplantation of mesenchymal stem cells promotes the functional recovery of the central nervous system following cerebral ischemia by inhibiting myelin-associated inhibitor expression and neural ..." in: Experimental and therapeutic medicine, Vol. 11, Issue 5, pp. 1595-1600, (2016) (PubMed).

Vontell, Supramaniam, Wyatt-Ashmead, Gressens, Rutherford, Hagberg, Thornton: "Cellular mechanisms of toll-like receptor-3 activation in the thalamus are associated with white matter injury in the developing brain." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 3, pp. 273-85, (2015) (PubMed).

Synonyms and alternative names related to Reticulon 4

reticulon 4 (RTN4), reticulon 4 (rtn4), reticulon 4 (Rtn4), reticulon 4a (rtn4a), 1110020G17Rik, AA407876, AA409940, AA960376, ASY, C130026I10Rik, DKFZp459C0314, mKIAA0886, mKIAA4153, Nbla00271, Nbla10545, NgA, NI-250, NI220/250, NOGO, Nogo, nogo, NOGO-A, Nogo-A, Nogo-B, Nogo-C, NOGOC, NSP, NSP-CL, r, rat N, rat NogoA, reticulon-4, RTN-X, rtn4, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C, RTN4-Cw, Vp20, wu:fb17a02, wu:fb22f12, wu:fd61a07, zgc:92163

Protein level used designations for Reticulon 4

  • Human NogoA
  • My043 protein
  • foocen
  • neurite growth inhibitor 220
  • neurite outgrowth inhibitor
  • neuroendocrine-specific protein C homolog
  • reticulon 5
  • reticulon-4
  • RTN4-Cw
  • reticulon 4
  • GLUT4 vesicle 20kDa protein
  • NI-220/250
  • glut4 vesicle 20 kDa protein
  • nogo protein
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