RENT2/UPF2 Products
(UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
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This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene\\\\; both variants encode the same protein. [provided by RefSeq, Jul 2008].
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Featured RENT2/UPF2 Categories
RENT2/UPF2 Antibodies
High quality antibodies with extensive validation data.
Recommended RENT2/UPF2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN6149941
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (2)
Cat. No.
ABIN654649
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN6570914
Quantity
200 μL
Datasheet
Datasheet
Recommended RENT2/UPF2 Proteins
Latest Publications for our RENT2/UPF2 products
: "Compound C inhibits nonsense-mediated RNA decay independently of AMPK." in: PLoS ONE, Vol. 13, Issue 10, pp. e0204978, (2019) (PubMed).: "Intracellular calcium regulates nonsense-mediated mRNA decay." in: Nature medicine, Vol. 20, Issue 8, pp. 961-6, (2014) (PubMed).
: "CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells." in: Nature structural & molecular biology, Vol. 12, Issue 10, pp. 893-901, (2005) (PubMed).
Synonyms and alternative names related to RENT2/UPF2
UPF2, regulator of nonsense mediated mRNA decay (UPF2), UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2), UPF2, regulator of nonsense mediated mRNA decay (Upf2), UPF2 regulator of nonsense transcripts homolog (yeast) (UPF2), UPF2 regulator of nonsense transcripts homolog (yeast) (upf2), HUPF2, RENT2, smg-3Protein level used designations for RENT2/UPF2
- nonsense mRNA reducing factor 2
- regulator of nonsense transcripts 2
- smg-3 homolog, nonsense mediated mRNA decay factor
- up-frameshift suppressor 2 homolog
- yeast Upf2p homolog
- UPF2 regulator of nonsense transcripts homolog (yeast)
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