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Renin Products

(Renin (REN))
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008].

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Featured Renin Categories

Renin Antibodies

High quality antibodies with extensive validation data.

Renin ELISA Kits

Reliable ELISA kits for a wide range of species.

Renin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Renin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7432865
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN562625
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7427696
Quantity 100 μL
Datasheet Datasheet

Recommended Renin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (6)
Cat. No. ABIN6574235
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (5)
Cat. No. ABIN6574236
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6963592
Quantity 96 tests
Datasheet Datasheet

Recommended Renin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320778
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317797
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320334
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Renin products

Juretzko, Steinbach, Witte, Hannemann, Miehe, Siegerist, Wolke, Stracke, Rettig: "Renal angiotensin I-converting enzyme-deficient mice are protected against aristolochic acid nephropathy." in: Pflugers Archiv : European journal of physiology, (2022) (PubMed).

Tata, Sewani-Rusike, Oyedeji, Mahlakata, Shauli, Nkeh-Chungag: "Senecio serratuloides extract prevents the development of hypertension, oxidative stress and dyslipidemia in nitric oxide-deficient rats." in: Journal of complementary & integrative medicine, Vol. 17, Issue 2, (2021) (PubMed).

García-Arroyo, Muñoz-Jiménez, Gonzaga, Tapia, Osorio-Alonso, Roncal-Jiménez, Iroz, Vecchio, Reyes-García, Johnson, Sánchez-Lozada: "A Role for Both V1a and V2 Receptors in Renal Heat Stress Injury Amplified by Rehydration with Fructose." in: International journal of molecular sciences, Vol. 20, Issue 22, (2020) (PubMed).

Buhl, Djudjaj, Klinkhammer, Ermert, Puelles, Lindenmeyer, Cohen, He, Borkham-Kamphorst, Weiskirchen, Denecke, Trairatphisan, Saez-Rodriguez, Huber, Olson, Floege, Boor: "Dysregulated mesenchymal PDGFR-β drives kidney fibrosis." in: EMBO molecular medicine, Vol. 12, Issue 3, pp. e11021, (2020) (PubMed).

Santos, de Bem, da Costa, de Carvalho, de Medeiros, Silva, Romão, de Andrade Soares, Ognibene, de Moura, Resende: "Açaí seed extract prevents the renin-angiotensin system activation, oxidative stress and inflammation in white adipose tissue of high-fat diet-fed mice." in: Nutrition research (New York, N.Y.), Vol. 79, pp. 35-49, (2020) (PubMed).

Yıldız, Baki, Özer: "Serum Renin Levels in Sudden Sensorineural Hearing Loss." in: The Annals of otology, rhinology, and laryngology, Vol. 129, Issue 8, pp. 806-812, (2020) (PubMed).

Vishnolia, Hoene, Tarhbalouti, Revenstorff, Aherrahrou, Erdmann: "Studies in Zebrafish Demonstrate That CNNM2 and NT5C2 Are Most Likely the Causal Genes at the Blood Pressure-Associated Locus on Human Chromosome 10q24.32." in: Frontiers in cardiovascular medicine, Vol. 7, pp. 135, (2020) (PubMed).

Dizaye, Mustafa: "The effect of eplerenone on the renin-angiotensin-aldosterone system of rats with thyroid dysfunction." in: The Journal of pharmacy and pharmacology, Vol. 71, Issue 12, pp. 1800-1808, (2020) (PubMed).

Kim, Do, Kim: "Activation of the renin-angiotensin system in high fructose-induced metabolic syndrome." in: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, Vol. 24, Issue 4, pp. 319-328, (2020) (PubMed).

Zhao, Tang, Xi, Huang, Zhang, Liu, Wang, Tang, Zhong, He: "Calcilytic NPS2143 promotes proliferation and inhibits apoptosis of spontaneously hypertensive rat vascular smooth muscle cells via activation of the renin-angiotensin system." in: Experimental and therapeutic medicine, Vol. 20, Issue 2, pp. 818-829, (2020) (PubMed).

Synonyms and alternative names related to Renin

renin (REN), renin (Ren), renin 1 structural (Ren1), renin (ren), D19352, HNFJ2, RATRENAA, Ren, Ren-1, Ren-A, Ren1, Ren1c, Ren1d, RENAA, Rn-1, Rnr

Protein level used designations for Renin

  • angiotensin-forming enzyme
  • angiotensinogenase
  • renin precursor, renal
  • prorenin
  • renin 1 structural
  • renin-like
  • preprorenin
  • Angiotensinogenase
  • aspartyl-protease
  • kidney renin
  • renin b
  • renin-1
  • cathepsin E
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