REG3D Protein (His tag)
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- Target
- REG3D (Regenerating Islet-Derived 3 delta (REG3D))
- Protein Type
- Recombinant
- Origin
- Mouse
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This REG3D protein is labelled with His tag.
- Purpose
- Recombinant Mouse REG3D Protein (His Tag)
- Sequence
- Met 1-Gly 175
- Characteristics
- A DNA sequence encoding the mouse REG3D isoform 1 (NP_038921.2) extracellular domain (Met 1-Gly 175) was fused with a polyhistidine tag at the C-terminus.
- Purity
- > 97 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- REG3D (Regenerating Islet-Derived 3 delta (REG3D))
- Alternative Name
- REG3D
- Synonyms
- INGAP Protein, Ingaprp Protein, regenerating islet-derived 3 delta Protein, Reg3d Protein
- Background
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Background: Regenerating islet-derived 3 delta (REG3D) is a member of the secreted Reg superfamily and contains one typical C-type lectin domain. Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family, which consists of four subtypes (types I, II, III, IV) based on the primary structures of the encoded proteins of the genes, which are associated with tissue repair and have been directly implicated in pancreatic beta-cell regeneration. Reg proteins are expressed in various organs and are involved in cancers and neurodegenerative diseases. They display a typical C-type lectin-like domain but possess additional highly conserved amino acids.
Synonym: INGAP,Ingaprp,MGC130575,Reg3d
- Molecular Weight
- 18.5 kDa
- NCBI Accession
- NP_038921
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