RCC1 Products
(Regulator of Chromosome Condensation 1 (RCC1))
Categories
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly.
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Featured RCC1 Categories
RCC1 Antibodies
High quality antibodies with extensive validation data.
RCC1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RCC1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (13)
Cat. No.
ABIN6146817
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN560352
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IP
Validations
- (5)
Cat. No.
ABIN514370
Quantity
100 μg
Datasheet
Datasheet
Recommended RCC1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207329
Quantity
96 tests
Datasheet
Datasheet
Recommended RCC1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317692
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317690
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2730653
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our RCC1 products
: "C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import." in: eLife, Vol. 9, (2020) (PubMed).: "Exercise attenuates age-associated changes in motoneuron number, nucleocytoplasmic transport proteins and neuromuscular health." in: GeroScience, Vol. 40, Issue 2, pp. 177-192, (2018) (PubMed).
: "Structure-dependent mitochondrial dysfunction and hypoxia induced with single-walled carbon nanotubes." in: Small (Weinheim an der Bergstrasse, Germany), Vol. 10, Issue 14, pp. 2859-69, (2014) (PubMed).
: "Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells." in: Genes & development, Vol. 18, Issue 5, pp. 512-27, (2004) (PubMed).
: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).
: "The dynamic association of RCC1 with chromatin is modulated by Ran-dependent nuclear transport." in: Molecular biology of the cell, Vol. 15, Issue 1, pp. 245-55, (2003) (PubMed).
: "Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrest." in: Molecular and cellular biology, Vol. 22, Issue 9, pp. 2993-3002, (2002) (PubMed).
: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).
: "Ran binds to chromatin by two distinct mechanisms." in: Current biology : CB, Vol. 12, Issue 13, pp. 1151-6, (2002) (PubMed).
: "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 17385-8, (2002) (PubMed).
Synonyms and alternative names related to RCC1
regulator of chromosome condensation 1 (rcc1), regulator of chromosome condensation 1 (RCC1), regulator of chromosome condensation 1 L homeolog (rcc1.L), Regulator of chromosome condensation 1 (Rcc1), N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted (RCC1), regulator of chromosome condensation 1 S homeolog (rcc1.S), regulator of chromosome condensation 1 (Rcc1), 4931417M11Rik, AI326872, BJ1, CG10480, CG18640 (Bj1), Chc1, CHC1, chc1-a, chc1-b, Dmel\\CG10480, dRCC1, inxs, MGC115703, MGC132085, RanGEF, rcc1, RCC1, Rcc1, RCC1-I, sdt, SNHG3-RCC1, wu:fj77f08, xrcc1, zgc:65796, zgc:77114Protein level used designations for RCC1
- chromosome condensation 1
- fj77f08
- regulator of chromosome condensation
- regulator of chromosome condensation 1
- RCC1 protein
- Bj1-PA
- Bj1-PB
- Bj1-PC
- CG10480-PA
- CG10480-PB
- CG10480-PC
- in excess
- side-out
- possible fragment of potential guanine nucleotide exchange factor
- SNHG3-RCC1 readthrough transcript
- cell cycle regulatory protein
- guanine nucleotide-releasing protein
- chromosome condensation protein 1
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