RBM25 Products
(RNA Binding Motif Protein 25 (RBM25))
Categories
RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA (By similarity).
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Featured RBM25 Categories
RBM25 Antibodies
High quality antibodies with extensive validation data.
Recommended RBM25 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN7270082
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IF
Validations
- (1)
Cat. No.
ABIN7258448
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6748334
Quantity
100 μL
Datasheet
Datasheet
Recommended RBM25 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207321
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our RBM25 products
: "Detecting endogenous SUMO targets in mammalian cells and tissues." in: Nature structural & molecular biology, Vol. 20, Issue 4, pp. 525-31, (2013) (PubMed).: "Nuclear cathepsin F regulates activation markers in rat hepatic stellate cells." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4238-48, (2008) (PubMed).
: "Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection." in: Molecular and cellular biology, Vol. 28, Issue 19, pp. 5924-36, (2008) (PubMed).
Synonyms and alternative names related to RBM25
RNA binding motif protein 25b (rbm25b), RNA binding motif protein 25 (Rbm25), RNA binding motif protein 25 S homeolog (rbm25.S), RNA binding motif protein 25 (rbm25), RNA binding motif protein 25 (RBM25), putative rna binding motif protein 25 (Smp_078610), 2600011C06Rik, 2610015J01Rik, A130095G20Rik, AI159652, AL023075, AU043498, fi03e10, fSAP94, NET52, RED120, rnpc7, RNPC7, s164, S164, si:ch211-105d18.5, Snu71, wu:fi03e10, zgc:56208Protein level used designations for RBM25
- RNA-binding protein 25
- RNA binding motif protein 25
- RNA-binding protein 25-like
- Arg/Glu/Asp-rich protein, 120 kDa
- RNA-binding motif protein 25
- RNA-binding region (RNP1, RRM) containing 7
- RNA-binding region-containing protein 7
- U1 small nuclear ribonucleoprotein 1SNRP homolog
- arg/Glu/Asp-rich protein of 120 kDa
- functional spliceosome-associated protein 94
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