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RASSF5 Products

(Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

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This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured RASSF5 Categories

RASSF5 Antibodies

High quality antibodies with extensive validation data.

RASSF5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RASSF5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7167138
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (p), IF (cc), ELISA, IHC (fro), IHC (p), ICC
Validations
  • (1)
  • (1)
Cat. No. ABIN1386228
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN566504
Quantity 50 μL
Datasheet Datasheet

Recommended RASSF5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317532
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317534
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094943
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RASSF5 products

Yang, Kong, Jin, Hergovich, Püschel: "Rassf5 and Ndr kinases regulate neuronal polarity through Par3 phosphorylation in a novel pathway." in: Journal of cell science, Vol. 127, Issue Pt 16, pp. 3463-76, (2014) (PubMed).

Donninger, Clark, Monaghan, Schmidt, Vos, Clark: "Cell cycle restriction is more important than apoptosis induction for RASSF1A protein tumor suppression." in: The Journal of biological chemistry, Vol. 289, Issue 45, pp. 31287-95, (2014) (PubMed).

Schmidt, Donninger, Clark: "Ras regulates SCF(β-TrCP) protein activity and specificity via its effector protein NORE1A." in: The Journal of biological chemistry, Vol. 289, Issue 45, pp. 31102-10, (2014) (PubMed).

Gezginci-Oktayoglu, Bolkent: "Ras signaling in NGF reduction and TNF-α-related pancreatic β cell apoptosis in hyperglycemic rats." in: Apoptosis : an international journal on programmed cell death, Vol. 17, Issue 1, pp. 14-24, (2012) (PubMed).

Calvisi, Donninger, Vos, Birrer, Gordon, Leaner, Clark: "NORE1A tumor suppressor candidate modulates p21CIP1 via p53." in: Cancer research, Vol. 69, Issue 11, pp. 4629-37, (2009) (PubMed).

Miertzschke, Stanley, Bunney, Rodrigues-Lima, Hogg, Katan: "Characterization of interactions of adapter protein RAPL/Nore1B with RAP GTPases and their role in T cell migration." in: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30629-42, (2007) (PubMed).

Synonyms and alternative names related to RASSF5

Ras association domain family member 5 (RASSF5), Ras association (RalGDS/AF-6) domain family member 5 (Rassf5), Ras association domain family member 5 (Rassf5), 1300019G20Rik, AU042887, Maxp1, NORE1, Nore1, NORE1A, Nore1A, NORE1B, Nore1B, RAPL, Rapl, RASSF3

Protein level used designations for RASSF5

  • Rap1-binding protein
  • Ras association (RalGDS/AF-6) domain family 5
  • Ras effector-like protein
  • new ras effector 1
  • novel Ras effector 1
  • ras association domain-containing protein 5
  • regulator for cell adhesion and polarization enriched in lymphoid tissue
  • tumor suppressor RASSF3
  • novel ras effector 1
  • regulator for cell adhesion and polarization enriched in lymphoid tissues
  • protein interacting with guanine nucleotide exchange factor
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