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RASGRF1 Products

(Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009].

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Featured RASGRF1 Categories

RASGRF1 Antibodies

High quality antibodies with extensive validation data.

RASGRF1 ELISA Kits

Reliable ELISA kits for a wide range of species.

RASGRF1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RASGRF1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (4)
Cat. No. ABIN2786746
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7167404
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN391841
Quantity 400 μL
Datasheet Datasheet

Recommended RASGRF1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1154833
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1154834
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1154835
Quantity 96 tests
Datasheet Datasheet

Recommended RASGRF1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317494
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095012
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3133523
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RASGRF1 products

Iguchi, Miyakawa, Saito, Nakabayashi, Nakanishi, Saya, Ikeda, Kizaki: "Zoledronate-induced S phase arrest and apoptosis accompanied by DNA damage and activation of the ATM/Chk1/cdc25 pathway in human osteosarcoma cells." in: International journal of oncology, Vol. 31, Issue 2, pp. 285-91, (2007) (PubMed).

Holmes, Chang, Soloway: "Timing and sequence requirements defined for embryonic maintenance of imprinted DNA methylation at Rasgrf1." in: Molecular and cellular biology, Vol. 26, Issue 24, pp. 9564-70, (2006) (PubMed).

Synonyms and alternative names related to RASGRF1

Ras protein specific guanine nucleotide releasing factor 1 (RASGRF1), RAS protein-specific guanine nucleotide-releasing factor 1 (Rasgrf1), Ras protein specific guanine nucleotide releasing factor 1 S homeolog (rasgrf1.S), si:ch211-234p18.3 (si:ch211-234p18.3), Ras protein specific guanine nucleotide releasing factor 1 (rasgrf1), Ras protein specific guanine nucleotide releasing factor 1 (Rasgrf1), AI844718, CDC25, cdc25, CDC25L, CDC25Mm, GNRP, GRF1, Grf1, GRF55, Grfbeta, H-GRF55, p190, P190-A, p190RhoGEF, PP13187, ras-GRF1, Ras-GRF1, rasgrf1

Protein level used designations for RASGRF1

  • Ras-specific guanine nucleotide-releasing factor, CDC25 homolog
  • Ras-specific nucleotide exchange factor CDC25
  • guanine nucleotide exchange factor
  • guanine nucleotide-releasing factor 1
  • guanine nucleotide-releasing factor, 55 kD
  • guanine nucleotide-releasing protein
  • ras-specific guanine nucleotide-releasing factor 1
  • GNRP
  • GRF beta
  • Ras guanine release factor beta
  • guanine nucleotide releasing factor 1
  • ras-specific nucleotide exchange factor CDC25
  • P140 RAS-GRF
  • ras-GRF1
  • Ras protein-specific guanine nucleotide-releasing factor 1
  • ras-specific guanine nucleotide-releasing factor 1-like
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