RASA4 Products
(RAS P21 Protein Activator 4 (RASA4))
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This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured RASA4 Categories
RASA4 Antibodies
High quality antibodies with extensive validation data.
Recommended RASA4 Antibodies
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Reactivity
Application
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Reactivity
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ABIN7167152
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Datasheet
Datasheet
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Cat. No.
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ABIN3094909
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Datasheet
Datasheet
Reactivity
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Datasheet
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Latest Publications for our RASA4 products
: "CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway." in: Current biology : CB, Vol. 11, Issue 12, pp. 981-6, (2001) (PubMed).Synonyms and alternative names related to RASA4
RAS p21 protein activator 4 (RASA4), RAS p21 protein activator 4 (Rasa4), AA793972, AW112107, BB079060, CAPRI, GAPL, mKIAA0538Protein level used designations for RASA4
- Ca2+-promoted Ras inactivator
- calcium-promoted Ras inactivator
- ras GTPase-activating protein 4
- rasGAP-activating-like protein 2
- Ca2+promoted Ras inactivator
- calcium-promoted RAS inactivator
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