RASA2 Products
(RAS P21 Protein Activator 2 (RASA2))
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The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein\; a compound suggested to function as a second messenger. [provided by RefSeq, Jul 2008].
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RASA2 Antibodies
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Recommended RASA2 Antibodies
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Latest Publications for our RASA2 products
: "Recurrent inactivating RASA2 mutations in melanoma. ..." in: Nature genetics, Vol. 47, Issue 12, pp. 1408-10, (2015) (PubMed).: "A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions." in: Molecular and cellular biology, Vol. 14, Issue 10, pp. 6879-85, (1994) (PubMed).
Synonyms and alternative names related to RASA2
RAS p21 protein activator 2 (RASA2), RAS p21 protein activator 2 (Rasa2), 5430433H21Rik, AA517451, AU023900, GAP1M, GAP1mProtein level used designations for RASA2
- GTPase-activating protein 1m
- GTPase-activating protein of RAS
- ras GTPase-activating protein 2
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