RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Products
(RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
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The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Categories
RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Antibodies
High quality antibodies with extensive validation data.
RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (4)
Cat. No.
ABIN656117
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN523644
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN564429
Quantity
50 μL
Datasheet
Datasheet
Recommended RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959050
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN422861
Quantity
96 tests
Datasheet
Datasheet
Recommended RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317498
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317496
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317497
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) products
: "The transcriptomic and proteomic landscapes of bone marrow and secondary lymphoid tissues." in: PLoS ONE, Vol. 9, Issue 12, pp. e115911, (2014) (PubMed).: "ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells." in: Journal of the American Society of Nephrology : JASN, Vol. 21, Issue 3, pp. 478-88, (2010) (PubMed).
: "Calcium-diacylglycerol guanine nucleotide exchange factor I gene mutations associated with loss of function in canine platelets." in: Translational research : the journal of laboratory and clinical medicine, Vol. 150, Issue 2, pp. 81-92, (2007) (PubMed).
: "Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1." in: The Journal of biological chemistry, Vol. 279, Issue 12, pp. 11875-81, (2004) (PubMed).
: "Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 12819-24, (2002) (PubMed).
: "A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2." in: The Journal of biological chemistry, Vol. 276, Issue 27, pp. 25568-81, (2001) (PubMed).
: "Guanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neurons." in: The Journal of comparative neurology, Vol. 437, Issue 4, pp. 398-407, (2001) (PubMed).
Synonyms and alternative names related to RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated)
RAS guanyl releasing protein 2 (RASGRP2), RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog (rasgrp2.S), RAS, guanyl releasing protein 2 (Rasgrp2), RAS guanyl releasing protein 2 (Rasgrp2), RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog (rasgrp2.L), CALDAG-GEFI, CalDAG-GEFI, Caldaggef1, CDC25L, RASGRP2, rasgrp2, xrasgrp2Protein level used designations for RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated)
- F25B3.3 kinase-like protein
- RAS guanyl nucleotide-releasing protein 2
- RAS guanyl-releasing protein 2
- calcium and DAG-regulated guanine nucleotide exchange factor I
- calcium and diacylglycerol-regulated guanine nucleotide exchange factor I
- cdc25-like protein
- guanine exchange factor MCG7
- hCDC25L
- RAS guanyl-releasing protein 2-A
- RAS guanyl releasing protein 2
- RAS guanyl releasing protein 2, isoform 3
- CalDAG-GEFI
- F25B3.3 kinase like protein
- RAP 1A protein-specific guanine nucleotide exchange factor 1
- RAS, guanyl releasing protein 2; RAP 1A protein-specific guanine nucleotide exchange factor 1; CalDAG-GEFI
- RAS, guanyl releasing protein 2
- calDAG-GEFI
- calcium diacylglycerol guanine nucleotide exchange factor I
- RAS guanyl-releasing protein 2-B
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