RAPTOR Products
(RAPTOR)
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This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
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Featured RAPTOR Categories
RAPTOR Antibodies
High quality antibodies with extensive validation data.
Recommended RAPTOR Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, DB, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN389879
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN3032434
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN700780
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our RAPTOR products
: "A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1." in: Molecular and cellular biology, Vol. 30, Issue 2, pp. 481-95, (2009) (PubMed).: "Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation." in: Circulation research, Vol. 101, Issue 6, pp. 560-9, (2007) (PubMed).
: "Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein." in: The Journal of general virology, Vol. 86, Issue Pt 2, pp. 405-12, (2005) (PubMed).
: "mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery." in: Cell, Vol. 110, Issue 2, pp. 163-75, (2002) (PubMed).
: "Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action." in: Cell, Vol. 110, Issue 2, pp. 177-89, (2002) (PubMed).
Synonyms and alternative names related to RAPTOR
regulatory associated protein of MTOR complex 1 (RPTOR), regulatory associated protein of MTOR, complex 1 (Rptor), 4932417H02Rik, KOG1, Mip1, mKIAA1303, Rap, Raptor, RGD1311784Protein level used designations for RAPTOR
- p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats
- raptor
- regulatory-associated protein of mTOR
- p150 target of rapamycin (TOR)-scaffold protein
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