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RAG2 Products

(Recombination Activating Gene 2 (RAG2))

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This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms. [provided by RefSeq, Jul 2008].

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Featured RAG2 Categories

RAG2 Antibodies

High quality antibodies with extensive validation data.

RAG2 ELISA Kits

Reliable ELISA kits for a wide range of species.

RAG2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RAG2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, IF, IHC (p), ICC
Validations
  • (4)
Cat. No. ABIN2856698
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN950151
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN519621
Quantity 100 μg
Datasheet Datasheet

Recommended RAG2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969857
Quantity 96 tests
Datasheet Datasheet
Reactivity Goat
Analytical Method
Validations
Cat. No. ABIN995325
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN995326
Quantity 96 tests
Datasheet Datasheet

Recommended RAG2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317323
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094940
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3133308
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RAG2 products

Nagawa, Hirose, Nishizumi, Nishihara, Sakano: "Joining mutants of RAG1 and RAG2 that demonstrate impaired interactions with the coding-end DNA." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 38360-8, (2004) (PubMed).

Synonyms and alternative names related to RAG2

recombination activating 2 (RAG2), recombination activating gene 2 (RAG2), recombination activating gene 2 (Rag2), recombination activating 2 (Rag2), recombination activating gene 2 (rag2), recombination activating gene 2 S homeolog (rag2.S), RAG-2, Rag-2, rag-2, zgc:136743

Protein level used designations for RAG2

  • recombination activating gene 2
  • recombination activating protein 2
  • V(D)J recombination-activating protein 2-like
  • V(D)J recombination-activating protein 2
  • recombinase activating gene 2
  • v(D)J recombination-activating protein 2
  • RAG-2
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