RAG2 Products
(Recombination Activating Gene 2 (RAG2))
Categories
This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms. [provided by RefSeq, Jul 2008].
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Featured RAG2 Categories
RAG2 Antibodies
High quality antibodies with extensive validation data.
RAG2 ELISA Kits
Reliable ELISA kits for a wide range of species.
RAG2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RAG2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, IF, IHC (p), ICC
Validations
- (4)
Cat. No.
ABIN2856698
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN950151
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN519621
Quantity
100 μg
Datasheet
Datasheet
Recommended RAG2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969857
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Goat
Analytical Method
Validations
Cat. No.
ABIN995325
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN995326
Quantity
96 tests
Datasheet
Datasheet
Recommended RAG2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317323
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094940
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3133308
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RAG2 products
: "Joining mutants of RAG1 and RAG2 that demonstrate impaired interactions with the coding-end DNA." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 38360-8, (2004) (PubMed).Synonyms and alternative names related to RAG2
recombination activating 2 (RAG2), recombination activating gene 2 (RAG2), recombination activating gene 2 (Rag2), recombination activating 2 (Rag2), recombination activating gene 2 (rag2), recombination activating gene 2 S homeolog (rag2.S), RAG-2, Rag-2, rag-2, zgc:136743Protein level used designations for RAG2
- recombination activating gene 2
- recombination activating protein 2
- V(D)J recombination-activating protein 2-like
- V(D)J recombination-activating protein 2
- recombinase activating gene 2
- v(D)J recombination-activating protein 2
- RAG-2
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