RAD21 Products
(RAD21 Homolog (RAD21))
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The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008].
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Featured RAD21 Categories
RAD21 Antibodies
High quality antibodies with extensive validation data.
RAD21 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RAD21 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IP, IHC (p), ICC
Validations
- (1)
- (7)
Cat. No.
ABIN2856242
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Rat
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (8)
Cat. No.
ABIN5542652
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP, ChIP
Validations
- (7)
Cat. No.
ABIN7269822
Quantity
100 μL
Datasheet
Datasheet
Recommended RAD21 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317272
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094930
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135430
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RAD21 products
: "Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells." in: Science advances, Vol. 6, Issue 25, pp. eaaz6699, (2020) (PubMed).: "Cut1/separase-dependent roles of multiple phosphorylation of fission yeast cohesion subunit Rad21 in post-replicative damage repair and mitosis." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 6, pp. 765-76, (2008) (PubMed).
: "Separase-mediated cleavage of cohesin at interphase is required for DNA repair." in: Nature, Vol. 430, Issue 7003, pp. 1044-8, (2004) (PubMed).
: "Linking sister chromatid cohesion and apoptosis: role of Rad21." in: Molecular and cellular biology, Vol. 22, Issue 23, pp. 8267-77, (2002) (PubMed).
: "Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis." in: Oncogene, Vol. 20, Issue 35, pp. 4817-26, (2001) (PubMed).
: "Human chromatid cohesin component hRad21 is phosphorylated in M phase and associated with metaphase centromeres." in: The Journal of biological chemistry, Vol. 276, Issue 7, pp. 5059-67, (2001) (PubMed).
: "Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation." in: The Journal of biological chemistry, Vol. 275, Issue 34, pp. 26576-81, (2000) (PubMed).
: "Derivation of a dysplasia index for epidermal neoplasia." in: Dermatology (Basel, Switzerland), Vol. 185, Issue 3, pp. 190-5, (1992) (PubMed).
Synonyms and alternative names related to RAD21
RAD21 cohesin complex component (RAD21), RAD21 cohesin complex component a (rad21a), RAD21 cohesin complex component L homeolog (rad21.L), RAD21 cohesin complex component (Rad21), RAD21 cohesin complex component S homeolog (rad21.S), R-spondin 2 (RSPO2), CDLS4, hHR21, HR21, hr21, HRAD21, MCD1, mcd1, mKIAA0078, nxp-1, NXP1, nxp1, rad21, SCC1, scc1, wu:fb55d02, wu:fb93f04, xrad21Protein level used designations for RAD21
- double-strand-break repair protein rad21 homolog
- RAD21 homolog (S. pombe)
- SCC1 homolog
- NXP-1
- nuclear matrix protein 1
- protein involved in DNA double-strand break repair
- sister chromatid cohesion 1
- PW29
- pokeweed agglutinin-binding protein 29
- RAD21 homolog
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